This 48th edition, including amendments adopted up to 31 December 2014, brings together into one volume essential documents concerning the governance of the World Health Organization, including the Constitution, Rules of Procedure of both the World Health Assembly and the Executive Board, as well as Financial and Staff Regulations. It also includes Regulations for Expert Advisory Panels and Committees and for Study and Scientific Groups, the texts of agreements with the United Nations and other agencies, the Convention on the Privileges and Immunities of the Specialized Agencies, the Statute of the International Agency for Research on Cancer, and the principles governing relations with nongovernmental organizations. It lists Members and Associate Members of the World Health Organization.

In response to the call of the 48th World Health Assembly for a substantial revision of the International Health Regulations, this new edition of the Regulations will enter into force on June 15, 2007. The purpose and scope of the Regulations are "to prevent, protect against, control and provide a public health response to the international spread of disease in ways that are commensurate with and restricted to public health risks, and which avoid unnecessary interference with international traffic and trade." The Regulations also cover certificates applicable to international travel and transport, and requirements for international ports, airports and ground crossings.

"The World Health Organization's history spans more than six decades. The past twenty years has been a particularly busy period in the organization's development, given the transition from international to global health cooperation and thus the need to adapt to major changes in its operating environment. Consequently, the WHO has been a direct part of new institutional arrangements and has shared in increased funding to provide for global health. It has also had to adapt its activities and programs in response to rival initiatives, leading to many changes--not only to the names of specific parts of the WHO but also to the nature of their activities. This second edition explores the organization's institutional complexity."--Back cover.