This assay may be used to measure gene mutation in yeast, a eukaryotic micro-organism. Strains of Saccharomyces cerevisiae have been developed which detect forward or reverse mutations. A variety of haploid and diploid strains of the yeast can be ...

The OECD Guidelines for the Testing of Chemicals are a collection of internationally agreed methods for testing the safety of chemicals and chemical preparations, including pesticides and industrial chemicals. This 2005 update contains 11 new and 3 revised guidelines.

Providing a concise, yet comprehensive, reference on all aspects of industrial exposures and toxicants; this book aids toxicologists, industrial hygienists, and occupational physicians to investigate workplace health problems. • Updates and expands coverage with new chapters covering regulatory toxicology, toxicity testing, physical hazards, high production volume (HPV) chemicals, and workplace drug use • Includes information on occupational and environmental sources of exposure, mammalian toxicology, industrial hygiene, medical management and ecotoxicology • Retains a succinct chapter format that has become the hallmark for the previous editions • Distils a vast amount of information into one resource for both academics and professionals

The one-stop resource for health protection professionals, environmental scientists and safety engineers. Since the entire 40-volume Ullmann's Encyclopedia is inaccessible to many readers - particularly individuals, smaller companies or institutes - all the information on industrial toxicology, ecotoxicology, process safety as well as occupational health and safety has been condensed into this convenient 2-volume set. Based on the latest online edition of Ullmann's containing articles never been before in print, this ready reference provides practical information on applying the science of toxicology in both the occupational and environmental setting, and explains the fundamentals necessary for an understanding of the effects of chemical hazards on humans and ecosystems. The detailed and meticulously edited articles have been written by renowned experts from industry and academia, and much of the information has been thoroughly revised. Alongside explanations of safety regulations and legal aspects, this set covers food additives, toxic agents as well as medical and therapeutical issues. Top-quality illustrations, clear diagrams and charts combined with an extensive use of tables enhance the presentation and provide a unique level of detail. Deeper insights into any given area of interest is offered by referenced contributions, while rapid access to a particular subject is enhanced by both a keyword and author index.

This book introduces readers to food safety assessment research on Genetically Modified Organisms (GMOs). As is broadly known, the main concerns about GM foods’ adverse effects on health are the nutrients, toxicity, allergenicity and unexpected effects. Before GMOs can be made commercially available, a comprehensive food safety assessment – taking these concerns into account – must first be performed. Exploring these aspects, the book is divided into two parts: the first part focuses on the safety assessment guidelines of the CAC, while the second highlights new methods used for the evaluation of GMOs’ safety. Offering an essential, practical guide, it will be of interest to researchers and graduate students in the fields of food science and public health.

Monitoring the environment is absolutely essential if we are to identify hazards to human health, to assess environmental cleanup efforts, and to prevent further degradation of the ecosystem. Biomonitors and biomarkers combined with chemical monitoring offer the only approach to making these assessments. Based on an International Association of Great Lakes Research conference, this book is intended for researchers who want to incorporate new and different technologies in their development of specifically-crafted monitors; students who are learning the field of biomonitoring; and regulatory agencies that want to consider newer technologies to replace inadequate and less powerful test regimes.

This assay may be used to measure mitotic recombination (gene conversion or crossingover) in yeast, a eukaryotic micro-organism. Crossing-over is generally assayed by the production of recessive homozygous colonies or sectors produced in a ...