OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442D: In Vitro Skin Sensitisation Assays addressing the Adverse Outcome Pathway Key Event on Keratinocyte activation
| Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442D: In Vitro Skin Sensitisation Assays addressing the Adverse Outcome Pathway Key Event on Keratinocyte activation PDF eBook |
| Author | OECD |
| Publisher | OECD Publishing |
| Pages | 67 |
| Release | 2018-06-27 |
| Genre | |
| ISBN | 9264229825 |
This Test Guideline (TG) provides an in vitro procedure (the ARE-Nrf2 luciferase test method) used for supporting the discrimination between skin sensitisers and non-sensitisers in accordance with the UN GHS.
Chemical Testing Using New Approach Methodologies (NAMs)
| Title | Chemical Testing Using New Approach Methodologies (NAMs) PDF eBook |
| Author | Amy J. Clippinger |
| Publisher | Frontiers Media SA |
| Pages | 139 |
| Release | 2022-12-16 |
| Genre | Science |
| ISBN | 2832508596 |
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442C: In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway key event on covalent binding to proteins
| Title | OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442C: In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway key event on covalent binding to proteins PDF eBook |
| Author | OECD |
| Publisher | OECD Publishing |
| Pages | 63 |
| Release | 2015-02-05 |
| Genre | |
| ISBN | 9264229701 |
This Test Guideline addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. It provides an in chemico procedure (Direct Peptide Reactivity Assay – DPRA) used for supporting the discrimination between skin sensitisers and non-sensitisers.
OECD Guidelines for the Testing of Chemicals, Section 4 Guideline No. 497: Defined Approaches on Skin Sensitisation
| Title | OECD Guidelines for the Testing of Chemicals, Section 4 Guideline No. 497: Defined Approaches on Skin Sensitisation PDF eBook |
| Author | OECD |
| Publisher | OECD Publishing |
| Pages | 53 |
| Release | 2023-07-04 |
| Genre | |
| ISBN | 9264903003 |
A Defined Approach (DA) consists of a selection of information sources (e.g in silico predictions, in chemico, in vitro data) used in a specific combination, and resulting data are interpreted using a fixed data interpretation procedure (DIP) (e.g. a mathematical, rule-based model). DAs use methods in combination and are intended to overcome some limitations of the individual, stand-alone methods.
Toxicity Mechanisms, Exposure, Toxicokinetic and Risk Assessment Aspects of Metals, Toxic for Animals and Humans
| Title | Toxicity Mechanisms, Exposure, Toxicokinetic and Risk Assessment Aspects of Metals, Toxic for Animals and Humans PDF eBook |
| Author | Yanzhu Zhu |
| Publisher | Frontiers Media SA |
| Pages | 263 |
| Release | 2022-03-10 |
| Genre | Science |
| ISBN | 2889746402 |
Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion
| Title | Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion PDF eBook |
| Author | OECD |
| Publisher | OECD Publishing |
| Pages | 15 |
| Release | 2006-08-17 |
| Genre | |
| ISBN | 9264067310 |
This Test Guideline is for an in vitro membrane barrier test method that can be used to identify corrosive substances. The test method utilizes an artificial membrane designed to respond to corrosive substances in a manner similar to animal skin in ...
Contact Dermatitis
| Title | Contact Dermatitis PDF eBook |
| Author | Peter J. Frosch |
| Publisher | Springer Science & Business Media |
| Pages | 1176 |
| Release | 2006 |
| Genre | Health & Fitness |
| ISBN | 9783540244714 |
Accompanying CD-ROM includes "all clinical photographs and important diagrams"--p. [vii].