This Test Guideline presents guidance for measurement of lethal and other observed effects in fish exposed to test substances. It may be used in place of Test Guideline 203 if a longer observation period is considered useful and appropriate and the ...

The OECD Guidelines for the Testing of Chemicals are a collection of internationally agreed methods for testing the safety of chemicals and chemical preparations, including pesticides and industrial chemicals. This 2005 update contains 11 new and 3 revised guidelines.

The OECD Guidelines for the Testing of Chemicals provide a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as the standard methods for safety testing, the OECD Guidelines for ...

Highlighting the major economic and industrial changes in the lubrication industry since the first edition, Synthetics, Mineral Oils, and Bio-Based Lubricants: Chemistry and Technology, Third Edition highlights the major economic and industrial changes in the lubrication industry and outlines the state of the art in each major lubricant application area. Chapters cover the use of lubricant fluids, growth or decline of market areas and applications, potential new applications, production capacities, and regulatory issues, including biodegradability, toxicity, and food production equipment lubrication. The highly-anticipated third edition features new and updated chapters including those on automatic and continuously variable transmission fluids, fluids for food-grade applications, oil-soluble polyalkylene glycols, functional bio-based lubricant base stocks, farnesene-derived polyolefins, estolides, bio-based lubricants from soybean oil, and trends in construction equipment lubrication. Features include: Contains an index of terms, acronyms, and analytical testing methods. Presents the latest conventions for describing upgraded mineral oil base fluids. Considers all the major lubrication areas: engine oils, industrial lubricants, food-grade applications, greases, and space-age applications Includes individual chapters on lubricant applications—such as environmentally friendly, disk drive, and magnetizable fluids—for major market areas around the globe. In a single, unique volume, Synthetics, Mineral Oils, and Bio-Based Lubricants: Chemistry and Technology, Third Edition offers property and performance information of fluids, theoretical and practical background to their current applications, and strong indicators for global market trends that will influence the industry for years to come.

A Comprehensive Review of Developing Environmentally Friendly Lubricants A push from environmentally savvy consumers along with recent changes in governmental regulations have paved the way for a marketplace of products with high levels of environmental performance. Fueled by the growing demand for biobased lubricants, Environmentally Friendly and Biobased Lubricants highlights the development of environmentally friendly additives that are compatible with environmental regulations and describes the approaches being used in this emerging area. Derived from research topics shared over the years at various technical sessions of the Society of Tribologists and Lubrication Engineers (STLE) Annual Meetings, the book includes a critical assessment of gaps and weaknesses in the field of environmentally friendly fluids and biobased lubricants. Each chapter is written by authors selected from the environmentally friendly fluids and biobased lubricants sessions of STLE and also incorporates input from prominent researchers invited to take part in the book. Expert contributors discuss the control, production, usage, and disposal of lubricants; factor in related policies, laws, and regulations around the world; and include case studies demonstrating the uses and values of commercially viable biobased lubricants. The book is divided into five sections that cover advanced environmentally friendly base oils and feedstocks, biobased hydraulic lubricants and biodegradability, chemically/enzymatically modified environmentally friendly base oils, vegetable oil–based environmentally friendly fluids, and additives for environmentally friendly fluids.

The workshop report reviews the options available for the analysis of data from ecotoxicity tests; compares their advantages and disadvantages; a recommends (a) the most appropriate approach for deriving summary parameter(s) and (b) further work to be undertaken.

This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.