Would you believe bee's venom could help you feel better? How about a candle in your ear, or a string running through your nostrils? People have used all sorts of kooky remedies to fight pain and illness. Some work. Others, not so much. Find out more about odd medical cures of past and present!

Would you believe bee's venom could help you feel better? How about a candle in your ear, or a string running through your nostrils? People have used all sorts of kooky remedies to fight pain and illness. Some work. Others, not so much. Find out more about odd medical cures of past and present!

Strange Medicine casts a gimlet eye on the practice of medicine through the ages that highlights the most dubious ideas, bizarre treatments, and biggest blunders. From bad science and oafish behavior to stomach-turning procedures that hurt more than helped, Strange Medicine presents strange but true facts and an honor roll of doctors, scientists, and dreamers who inadvertently turned the clock of medicine backward: • The ancient Egyptians applied electric eels to cure gout. • Medieval dentists burned candles in patients’ mouths to kill invisible worms gnawing at their teeth. • Renaissance physicians timed surgical procedures according to the position of the stars, and instructed epileptics to collect fresh blood from the newly beheaded. • Dr. Walter Freeman, the world’s foremost practitioner of lobotomies, practiced his craft while traveling on family camping trips, cramming the back of the station wagon with kids—and surgical tools—then hammering ice picks into the eye sockets of his patients in between hikes in the woods. Strange Medicine is an illuminating panorama of medical history as you’ve never seen it before.

It's easy to take a pill when we aren't feeling well. But did you know that the art of making medicines goes back thousands of years? Early remedies weren't always so easy—or effective. Some seemed downright disgusting. Wine infused with a venomous snake was used to cure fatigue and hair loss. Snail slime soothed burns, and a mixture of ear wax and mud treated headaches. Discover more about how medicine was practiced centuries ago and how, eventually, scientists discovered some truly amazing remedies, from the magic bullet that treated syphilis to the insulin used for diabetes.

The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

It wasn’t too long ago that people tried all sorts of things to help sick people feel better. They tried wild things like drinking a glass full of millipedes or putting some mustard on one's head. Some of the cures worked, and some of them…well, let’s just say that millipedes, living or dead, are not meant to be ingested. Carlyn Beccia takes readers on a colorful and funny medical mystery tour to discover that while times may have changed, many of today’s most reliable cure-alls have their roots in some very peculiar practices, and so relevant connections can be drawn from what they did then to what we do now.

Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.