Childbed fever was by the far the most common cause of deaths associated with childbirth up to the Second World War throughout Britain and Europe. Otherwise known as puerperal fever, it was an infection which followed childbirth and caused thousands of miserable and agonising deaths every year. This book provides the first comprehensive account of this tragic disease from its recognition in the eighteenth century up to the second half of the twentieth century. Examining this within a broad history of infective diseases, the author goes on to explore ideas from past debates about the nature of infectious diseases and contagion, the discovery of bacteria and antisepsis, and charts the complicated path which led to the discovery of antibiotics. The large majority of deaths from puerperal fever were due to one micro-organism known as Streptococcus pyogenes, and the last chapter presents valuable new ideas on the nature and epidemiology of streptococcal disease up to the present day.

Semmelweis's exposure to the childbed fever was concurrent with his appointment to the Vienna maternity hospital in 1846. Like many similar hospitals and clinics in the major cities of nineteenth-century Europe and America, where death rates from the illness sometimes climbed as high as 40 percent of admitted patients, the Viennese wards were ravaged by the fever. Intensely troubled by the tragic and baffling loss of so many young mothers, Semmelweis sought answers. The Etiology was testimony to his success. Based on overwhelming personal evidence, it constituted a classic description of a disease, its causes, and its prevention. It also allowed a necessary response to the obstetrician's already vocal, rabid, and perhaps predictable critics. For Semmelweis's central thesis was a startling one - the fever, he correctly surmised, was caused not by epidemic or endemic influences but by unsterilized and thus often contaminated hands of the attending physicians themselves.