Nunn's Applied Respiratory Physiology

This is a text for anaesthetists, physiologists and anyone seeking information about the basic principles and applications of lung function. This edition has been revised to include new scientific findings.

Nunn's Applied Respiratory Physiology, Seventh Edition covers all aspects of respiratory physiology in health, disease, and altered conditions and environments, from basic science to clinical applications. Includes functional anatomy, mechanics, control of breathing, ventilation, circulation, ventilation-perfusion matching, diffusion, carbon dioxide and oxygen, and non-respiratory functions of the lung. Discusses the effects of pregnancy, exercise, sleep, altitude, pressure, drowning, smoking, anaesthesia, hypocapnia, hypercarbia, hypoxia, hyperoxia, and anaemia on respiratory physiology. Explores specific clinical disorders such as ventilatory failure, airways disease, pulmonary vascular disease, parenchymal lung disease, and acute lung injury, as well as the physiological basis of current therapies, including artificial ventilation, extrapulmonary gas exchange, and lung transplantation. Chapter on Parenchymal Lung Disease has been specifically expanded to include the physiology and pathology of the pleural space and lung cancer. Contains a new chapter on Pulmonary Surgery, covering a wide range of surgical interventions from bronchoscopy to lung resection. Includes almost 500 new references to the literature. The result is an invaluable source for those preparing for examinations in anaesthesia and intensive care, as well as an essential purchase for practitioners who want quick reference to current knowledge. Describes respiration in health and disease and in normal and abnormal situations, to help readers manage all conditions they see in their practices. Examines the respiratory effects of exercise, sleep, smoking, anaesthesia, drowning, anaemia, pregnancy, and other events as well as environmental factors such as altitude, flying, high pressure, closed environments, and air pollution on respiration. Maintains the clarity of style and single-author approach of previous editions through the close collaboration of Andrew Lumb and John Nunn. Makes difficult concepts easy to understand and apply with nearly 300 illustrations. A new chapter on the History of Respiratory Physiology. More coverage of pathophysiology and even more applications of respiratory physiology to clinical practice. A more consistent organization, a revised page design that aids readability, and an art program featuring new and newly redrawn illustrations.

Nunn's Applied Respiratory Physiology, Eighth Edition, is your concise, one-stop guide to all aspects of respiratory physiology in health, disease, and in the many physiologically challenging situations and environments into which humans take themselves – with coverage from basic science to clinical applications. This most comprehensive single volume on respiratory physiology will be invaluable to those in training or preparing for examinations in anaesthesia, intensive care, respiratory medicine or thoracic surgery – as well as an essential quick reference for the range of practitioners requiring ready access to current knowledge in this field. Now fully revised and updated, this eighth edition includes a new full-colour format to improve clarity and understanding – and it also comes with access to the complete, downloadable eBook version for the first time. This incorporates bonus chapters, handy topic summaries and new, interactive, self-assessment material. The result is a more flexible, engaging and complete resource than ever before. Enhancements to this edition include: - New full colour format - enhances the 250+ diagrams and allows a much clearer portrayal of physiological concepts - New figures reflect modern functional imaging techniques - which are now able to generate detailed pictures of lung ventilation and perfusion in humans - A new section on the aims, effects and physiological basis of respiratory physiotherapy - to help both physiotherapists and doctors better understand this common intervention for treating patients' respiratory disease - Additional information on the significant impact of obesity on respiratory physiology in both health and disease - New sections on comparative respiratory physiology and respiratory physiology in veterinary practice - understanding respiration in less complex animals and the place of human respiration within the animal kingdom will be of interest to students/practitioners in biology, zoology or veterinary medicine, as well as enlightening in other contexts - Bonus eBook access – (printed book) includes access to the complete, fully searchable electronic text, via Expert Consult – incoporating extra chapters, handy chapter summaries and new self-assessment material to aid exam preparation Key features include: - The three-part structure of pure physiology (basic principles), applied physiology and physiology of respiratory disease is retained - Use of clear, simple diagrams to illustrate the material. - Duplication of US and rest-of-the-world units - References to recent research material to allow readers to explore topics in more depth

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The first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.