Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy
Title | Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy PDF eBook |
Author | Dale Jonathan Waterhouse |
Publisher | Springer |
Pages | 142 |
Release | 2019-07-09 |
Genre | Science |
ISBN | 3030214818 |
This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications.
Diagnostic Endoscopy
Title | Diagnostic Endoscopy PDF eBook |
Author | Haishan Zeng |
Publisher | Taylor & Francis |
Pages | 272 |
Release | 2013-12-09 |
Genre | Medical |
ISBN | 1420083473 |
Combining a professional development course on diagnostic endoscopy from SPIE (the international society advancing light-based research) and the authors' graduate course on biomedical optics, this work is written for researchers in medical optics and biomedical engineering as well as graduate medical optics students. It uses extensive examples/case
Sources of Medical Technology
Title | Sources of Medical Technology PDF eBook |
Author | Institute of Medicine |
Publisher | National Academies Press |
Pages | 254 |
Release | 1995-01-01 |
Genre | Medical |
ISBN | 0309176689 |
Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.
Endoscopy
Title | Endoscopy PDF eBook |
Author | Costin Teodor Streba |
Publisher | BoD – Books on Demand |
Pages | 152 |
Release | 2019-03-06 |
Genre | Medical |
ISBN | 1789851254 |
Endoscopic techniques are widely used for screening, diagnostic and therapeutic maneuvers in all groups of patients and for a large spectrum of complaints. The availability of basic iterations of endoscopic techniques made screening programs for various diseases viable in most parts of the world, while the advent of modern techniques opens new perspectives for rapid and correct diagnosis. Going beyond normal human vision, innovative techniques opened the prospect of in-situ pathology. Endoscopic ultrasound has made incredible progress in recent years. Reaching the smaller orifices by endoscopy was a major step forward in the surveillance of previously inaccessible lesions. Investigatory techniques were complemented by advances in therapy, with novel applications in many major areas of medicine.
Optical Detection of Cancer
Title | Optical Detection of Cancer PDF eBook |
Author | Arlen D. Meyers |
Publisher | World Scientific |
Pages | 206 |
Release | 2011-04-30 |
Genre | Technology & Engineering |
ISBN | 981429540X |
Significant progress in engineering has allowed the production of devices that can optically detect, differentiate and treat surface or near-surface cancers. The ability to differentiate cancerous from non-cancerous tissue in vitro using light represents a potentially significant advance in patient care, eliminating needless repeat procedures. With the help of advanced optical technologies, clinicians are able to identify cancers earlier, determine surgical margins at the time of surgery, and monitor treatment results without using expensive and insensitive imaging. This volume describes the state-of-the-art optical detection technologies in varying stages of cancer development. Written by an international panel of basic researchers, engineers and clinicians, the book is designed to give an up-to-date overview of the most recent advances for researchers and medical professionals who are interested in the biophotonic detection of cancer.
Endoscopy - Novel Techniques and Recent Advancements
Title | Endoscopy - Novel Techniques and Recent Advancements PDF eBook |
Author | Cristin Constantin Vere |
Publisher | |
Pages | 150 |
Release | 2019 |
Genre | Medical physics. Medical radiology. Nuclear medicine |
ISBN | 9781789851267 |
Endoscopic techniques are widely used for screening, diagnostic and therapeutic maneuvers in all groups of patients and for a large spectrum of complaints. The availability of basic iterations of endoscopic techniques made screening programs for various diseases viable in most parts of the world, while the advent of modern techniques opens new perspectives for rapid and correct diagnosis. Going beyond normal human vision, innovative techniques opened the prospect of in-situ pathology. Endoscopic ultrasound has made incredible progress in recent years. Reaching the smaller orifices by endoscopy was a major step forward in the surveillance of previously inaccessible lesions. Investigatory techniques were complemented by advances in therapy, with novel applications in many major areas of medicine.
Endoscopy in Early Gastrointestinal Cancers, Volume 2
Title | Endoscopy in Early Gastrointestinal Cancers, Volume 2 PDF eBook |
Author | Philip W. Y. Chiu |
Publisher | |
Pages | 0 |
Release | 2021 |
Genre | |
ISBN | 9789811067792 |
Endoscopy in Early Gastrointestinal Cancers, Volume 2: Treatment covers the detailed information of the indications, techniques and perioperative management of endoscopic resection including endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD). Carcinoma of the gastrointestinal tract remained a major health issue worldwide, which is, however notoriously difficult to treat. Endoscopic resection for early neoplasia of the gastrointestinal tract had been developed for more than 25 years. Endoscopic submucosal dissection (ESD) is a recently developed technique pioneer by Japanese endoscopists. The principle of ESD is to achieve a complete resection of gastrointestinal neoplasia limited to mucosa with adequate circumferential margins. This novel endoscopic technique not only allows the achievement of en-bloc resection for early GI cancers, it also conveys a significantly lower rate of local recurrence as compared to EMR for early gastric cancers. There is an urge for the knowledge in applying these novel technologies for the treatment of early GI neoplasia worldwide. This book on the endoscopic treatment of early GI neoplasia, containing lots of illustrations, artwork and numerous short video clips, serves as a bridge between the recent development in endoscopy and the knowledge of gastroenterologist, endoscopist and surgeons.