Novel Insights into Inflammatory Roles of Mast Cells and Basophils
Title | Novel Insights into Inflammatory Roles of Mast Cells and Basophils PDF eBook |
Author | Satoshi Tanaka |
Publisher | Frontiers Media SA |
Pages | 353 |
Release | 2023-04-20 |
Genre | Medical |
ISBN | 2832521215 |
Signal Transduction in Mast Cells and Basophils
Title | Signal Transduction in Mast Cells and Basophils PDF eBook |
Author | Ehud Razin |
Publisher | Springer Science & Business Media |
Pages | 454 |
Release | 1999-05-11 |
Genre | Medical |
ISBN | 9780387986258 |
Mast cells and basophils are responsible for inflammatory and allergic reactions. As such, the signals that generate these responses and how their pathways of action work are the focus of much present day research into allergy and inflammation. This book focuses primarily on the molecular mechanisms that govern mast cell and basophil cell biology and function, as well as providing a comprehensive summary of the field of signal transduction and also giving insights into areas that have therapeutic potential. The book provides detailed insights into mast cell and basophil growth and development, their activation by allergens, including details of receptor activation and downstream events, and the regulators of morphology and degranulation. The metabolic pathways involved in prostaglandin and leukotriene production are discussed as is the role of transcription factors in mast cell growth and cytokine production. Written by leaders in the field, this volume will provide the reader with an up-to-date account of a topic where the rapid progress makes conventional information gathering difficult.
Basophil and Mast Cell Degranulation and Recovery
Title | Basophil and Mast Cell Degranulation and Recovery PDF eBook |
Author | Ann M. Dvorak |
Publisher | Springer Science & Business Media |
Pages | 436 |
Release | 1991-08-31 |
Genre | Medical |
ISBN | 9780306437526 |
Basophils and mast cells are similar but unique secretory cells with a well-documented role in immediate-hypersensitivity reactions. The presence of these cells in various cell mediated hypersensitivity reactions, in tissues of multiple diseases, and as a component of the host reaction to injury and repair in numerous circumstances is well known. Release of stored and newly generated mediators of inflammation from basophils and mast cells contributes to the cascade of pathogenetic events in circumstances under which these release reactions occur. Despite insights acquired through studies of these pathologic events, the role of basophils and mast cells and their secretory products in health is not known. In this book, I review much of the structural information regarding basophils and mast cells of multiple species. Ultrastructural studies of rat mast cells historically precede and quantitatively exceed similar studies of basophils and mast cells of other species. Therefore, I first review these background studies as an entity. Then I discuss the contents of two prominent organelles-granules and lipid bodies-in basophils and mast cells of several species. The ultrastructural morphology of basophils and mast cells in three species is presented in detail to establish appropriate guidelines for their recognition and to provide general rules for analysis which are appropriate for the identification of these cells in other species as well.
Mast Cells in Chronic Inflammatory Diseases
Title | Mast Cells in Chronic Inflammatory Diseases PDF eBook |
Author | Ricardo Filipe Da Silva Carvalho |
Publisher | |
Pages | 44 |
Release | 2008 |
Genre | |
ISBN | 9789174091557 |
Mast Cell Biology
Title | Mast Cell Biology PDF eBook |
Author | Alasdair M. Gilfillan |
Publisher | Springer Science & Business Media |
Pages | 312 |
Release | 2011-06-28 |
Genre | Medical |
ISBN | 1441995331 |
The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
Mast Cells and Basophils
Title | Mast Cells and Basophils PDF eBook |
Author | Gianni Marone |
Publisher | Academic Press |
Pages | 738 |
Release | 2000-05-25 |
Genre | Medical |
ISBN | 0080535852 |
Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.
The Immune Escape Mechanism and Novel Immunotherapeutic Strategies of Leukemia
Title | The Immune Escape Mechanism and Novel Immunotherapeutic Strategies of Leukemia PDF eBook |
Author | Shenghui Zhang |
Publisher | Frontiers Media SA |
Pages | 177 |
Release | 2023-05-02 |
Genre | Medical |
ISBN | 2832522017 |