- Coherent and unified treatment of nonlinear regression with R. - Example-based approach. - Wide area of application.

Statistical Tools for Nonlinear Regression presents methods for analyzing data. It has been expanded to include binomial, multinomial and Poisson non-linear models. The examples are analyzed with the free software nls2 updated to deal with the new models included in the second edition. The nls2 package is implemented in S-PLUS and R. Several additional tools are included in the package for calculating confidence regions for functions of parameters or calibration intervals, using classical methodology or bootstrap.

Univariate nonlinear regression; Univariate nonlinear regression: special situations; A unified asymptotic theory of nonlinear models with regression structure; Univariate nonlinear regression: asymptotic theory; Multivariate nonlinear regression; Nonlinear simultaneus equations models; A unified asymptotic theory for dynamic nonlinear models.

Provides a presentation of the theoretical, practical, and computational aspects of nonlinear regression. There is background material on linear regression, including a geometrical development for linear and nonlinear least squares.

Since mathematical models express our understanding of how nature behaves, we use them to validate our understanding of the fundamentals about systems (which could be processes, equipment, procedures, devices, or products). Also, when validated, the model is useful for engineering applications related to diagnosis, design, and optimization. First, we postulate a mechanism, then derive a model grounded in that mechanistic understanding. If the model does not fit the data, our understanding of the mechanism was wrong or incomplete. Patterns in the residuals can guide model improvement. Alternately, when the model fits the data, our understanding is sufficient and confidently functional for engineering applications. This book details methods of nonlinear regression, computational algorithms,model validation, interpretation of residuals, and useful experimental design. The focus is on practical applications, with relevant methods supported by fundamental analysis. This book will assist either the academic or industrial practitioner to properly classify the system, choose between the various available modeling options and regression objectives, design experiments to obtain data capturing critical system behaviors, fit the model parameters based on that data, and statistically characterize the resulting model. The author has used the material in the undergraduate unit operations lab course and in advanced control applications.

Most biologists use nonlinear regression more than any other statistical technique, but there are very few places to learn about curve-fitting. This book, by the author of the very successful Intuitive Biostatistics, addresses this relatively focused need of an extraordinarily broad range of scientists.

Multivariate analysis is a popular area in statistics and data science. This book provides a good balance between conceptual understanding, key theoretical presentation, and detailed implementation with software R for commonly used multivariate analysis models and methods in practice.