Our scientific approach to depression depends on the theoretical framework available for depression and its etiology, and on the tools we have to investigate brain function. The implication of this means that models of depression will change with time. This book brings together recent updates on the main themes of depression research, presented by active researchers. This book will be of immense value to researchers working in the field, as well as clinicians and trainees in understanding the rationale of new diagnostic and treatment approaches. Biologists, pharmacologists and physicians will also benefit from the data on current depression research.

Integrative Therapies for Depression: Redefining Models for Assessment, Treatment and Prevention summarizes emerging theories and research findings on various nonpharmaceutical therapies to treat mood disorders.Supported by the review of nearly 3000 scientific studies, the book describes the concepts of inflammation, genetics, hormonal imbalance, g

Depression is a widespread condition affecting approximately 7.5 million parents in the U.S. each year and may be putting at least 15 million children at risk for adverse health outcomes. Based on evidentiary studies, major depression in either parent can interfere with parenting quality and increase the risk of children developing mental, behavioral and social problems. Depression in Parents, Parenting, and Children highlights disparities in the prevalence, identification, treatment, and prevention of parental depression among different sociodemographic populations. It also outlines strategies for effective intervention and identifies the need for a more interdisciplinary approach that takes biological, psychological, behavioral, interpersonal, and social contexts into consideration. A major challenge to the effective management of parental depression is developing a treatment and prevention strategy that can be introduced within a two-generation framework, conducive for parents and their children. Thus far, both the federal and state response to the problem has been fragmented, poorly funded, and lacking proper oversight. This study examines options for widespread implementation of best practices as well as strategies that can be effective in diverse service settings for diverse populations of children and their families. The delivery of adequate screening and successful detection and treatment of a depressive illness and prevention of its effects on parenting and the health of children is a formidable challenge to modern health care systems. This study offers seven solid recommendations designed to increase awareness about and remove barriers to care for both the depressed adult and prevention of effects in the child. The report will be of particular interest to federal health officers, mental and behavioral health providers in diverse parts of health care delivery systems, health policy staff, state legislators, and the general public.

Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Animal models represent experimental investigations developed in one species for the purpose of studying phenomena in another species and provide numerous advantages for preclinical research. They allow scientists greater control and isolation of important experimental variables. Animal models are safe, reproducible strategies by which to evaluate and design new pharma cological treatment strategies, while also allowing direct central nervous system intervention to alter the course of the aberrant behavior. Animal models have been developed for a number of mental illnesses; in this particular domain, they hold the promise to shed light on the still obscure etiologies of these illnesses and ultimately to facilitate the development and testing of "cures. " Yet, true models of mental illness are difficult to develop, because mental illness may be a uniquely human phenomenon. It was based on these considerations that the MacArthur Foundation Research Network on the Psychobiology of Depression set out to sponsor a conference to review the status, problems, promises, and relevance of animal models to the clinical conditions of affective disorders. The conference was held in September 1986 and included participants from both within the Network as well as scientists and scholars from various disciplines relevant to the concerns of the conference. After the conference was held, it became clear to the organizers that the material presented could be helpful to a broader field of investigators, since a significant portion of the information has not been presented elsewhere or in the unified context of a monograph.

This acclaimed work, now in a new edition, has introduced tens of thousands of clinicians to mindfulness-based cognitive therapy (MBCT) for depression, an 8-week program with proven effectiveness. Step by step, the authors explain the "whys" and "how-tos" of conducting mindfulness practices and cognitive interventions that have been shown to bolster recovery from depression and prevent relapse. Clinicians are also guided to practice mindfulness themselves, an essential prerequisite to teaching others. Forty-five reproducible handouts are included. Purchasers get access to a companion website featuring downloadable audio recordings of the guided mindfulness practices (meditations and mindful movement), plus all of the reproducibles, ready to download and print in a convenient 8 1/2" x 11" size. A separate website for use by clients features the audio recordings only. New to This Edition *Incorporates a decade's worth of developments in MBCT clinical practice and training. *Chapters on additional treatment components: the pre-course interview and optional full-day retreat. *Chapters on self-compassion, the inquiry process, and the three-minute breathing space. *Findings from multiple studies of MBCT's effectiveness and underlying mechanisms. Includes studies of adaptations for treating psychological and physical health problems other than depression. *Audio files of the guided mindfulness practices, narrated by the authors, on two separate Web pages--one for professionals, together with the reproducibles, and one just for clients. See also the authors' related titles for clients: The Mindful Way through Depression demonstrates these proven strategies in a self-help format, with in-depth stories and examples. The Mindful Way Workbook gives clients additional, explicit support for building their mindfulness practice, following the sequence of the MBCT program. Plus, for professionals: Mindfulness-Based Cognitive Therapy with People at Risk of Suicide extends and refines MBCT for clients with suicidal depression.

This bestselling, classic work offers a definitive presentation of the theory and practice of cognitive therapy for depression. Aaron T. Beck and his associates set forth their seminal argument that depression arises from a "cognitive triad" of errors and from the idiosyncratic way that one infers, recollects, and generalizes. From the initial interview to termination, many helpful case examples demonstrate how cognitive-behavioral interventions can loosen the grip of "depressogenic" thoughts and assumptions. Guidance is provided for working with individuals and groups to address the full range of problems that patients face, including suicidal ideation and possible relapse.