Ch. 1. 21st century challenges for biomaterials / Larry L. Hench -- ch. 2. Stem cell technology: hope or hype? / Larry L. Hench and Julian R. Jones -- ch. 3. Bioactive materials for gene control / Larry L. Hench -- ch. 4. Nanoparticles for novel healthcare therapeutics / Sudipta Seal [und weitere] -- ch. 5. Glass microspheres for cancer treatment / Delbert E. Day -- ch. 6. Bioactive glasses and angiogenesis / Alejandro A. Gorustovich, Luis A. Haro Durand, Aldo R. Boccaccini -- ch. 7. Clinical applications of bioactive glasses for maxillo-facial repair / Ian Thompson -- ch. 8. Clinical applications of bioactive glass-ceramics / Takao Yamamuro -- ch. 9. Hierarchical porous scaffolds for bone regeneration / Julian R. Jones -- ch. 10. Cartilage regeneration / Adam C. Grochowski and MIchael B. Fenn -- ch. 11. Hydrogels for tissue engineering of articular cartilage / Javier S. Castro -- ch. 12. Total knee replacements / Jason Wertz -- ch. 13. Total hip replacement / Kim Elshot Alvarez -- ch. 14. Bioactive surfaces for total hip prosthesis / Takao Yamamuro -- ch. 15. Artificial skin and wound dressings / Krystle Placencio [und weitere] -- ch. 16. Degenerative disc disease in the lumbar spine / Russell Beal -- ch. 17. Shoulder repair / Shane D. Smith -- ch. 18. Drug-eluting stents: worth the risk? / Adam Estelle -- ch. 19. Treating aortic aneurysms / Rochellee Manygoats -- ch. 20. Abdominal aortic aneurysms: treatment and repair / John Ashton -- ch. 21. Heart valve stenosis and surgical repair: present and future / Scott Cooper -- ch. 22. Prosthetic vascular grants for treatment of peripheral arterial disease / Margo Ellis -- ch. 23. Small-diameter vascular grafts / Kyle Marr -- ch. 24. Spinal cord repair: current methods and limitations / Julie Lockwood -- ch. 25. Spinal cord repair for paraplegics / Jeffrey Calhoun -- ch. 26. Brain-machine interfaces / Matthew Goodman -- ch. 27. Stem cell research for treatment of Parkinson's disease / Colleen Young and Michael B. Fenn -- ch. 28. Tissue engineering for corneal regeneration / Ayyasamy Aruchamy -- ch. 29. Development of Lasik: laser-assisted in situ keratomileusis -- ch. 30. Hearing devices: experiencing a world of sound / Savannah Burnside -- ch. 31. Glass-ceramic dental restorations / Wolfram Holand and Volker M. Rheinberger -- ch. 32. Pain-desensitizing dental materials / David C. Greenspan -- ch. 33. Ethical considerations in biomaterials research and development / Mrinal K. Musiband and Subrata Saha -- ch. 34. The ending / Larry L. Hench

Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

This text will draw on expertise of leading medical practitioners and researchers who utilise technologies to enhance patient outcomes. Research and practical evidence will be presented with a strong applied emphasis to further enhance the use of everyday technology within an array of specialisms in medicine.

Improving healthcare and staying healthy is one of the most discussed and important issues in our society. Technology has played and will play an important role in many aspects of the healthcare system, and it offers new and better ways to solve the key health problems of the new century. This book describes valued contributions of technology for improving hospital and home healthcare, and gives a perspective on how they will influence critical aspects of future medical care. It provides an overview and discussion of trends, presents the state-of-the-art of important research areas, and highlights recent breakthrough results in selected fields, giving an outlook on game-changing developments in the coming decades. The material is arranged in 6 parts and a total of 31 chapters. The healthcare areas addressed are: General advances and trends in healthcare technology, diagnostic imaging, integration of imaging and therapy, molecular medicine, medical information technology and personal healthcare.

Bioinspired Materials for Medical Applications examines the inspiration of natural materials and their interpretation as modern biomaterials. With a strong focus on therapeutic and diagnostic applications, the book also examines the development and manipulation of bioinspired materials in regenerative medicine. The first set of chapters is heavily focused on bioinspired solutions for the delivery of drugs and therapeutics that also offer information on the fundamentals of these materials. Chapters in part two concentrate on bioinspired materials for diagnosis applications with a wide coverage of sensor and imaging systems With a broad coverage of the applications of bioinspired biomaterials, this book is a valuable resource for biomaterials researchers, clinicians, and scientists in academia and industry, and all those who wish to broaden their knowledge in the allied field. - Explores how materials designed and produced with inspiration from nature can be used to enhance man-made biomaterials and medical devices - Brings together the two fields of biomaterials and bioinspired materials - Written by a world-class team of research scientists, engineers, and clinicians

Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. - Highlights different data techniques in healthcare data analysis, including machine learning and data mining - Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks - Includes applications and case studies across all areas of AI in healthcare data

In this book, Nigeria, the most populous country in Africa and a region in the lowest income group per capita, is used to demonstrate the potential for healthcare reorganization and collaboration with the introduction of “successful” technologies centered around available, bio-compatible, and sustainable natural resources. Our book discusses three of the top killers of children under 5 years of age in Nigeria, pneumonia (20%), diarrheal diseases (15%), and traumatic injuries (4%). These conditions are used as examples to demonstrate the potential for improved pediatric outcomes with treatments engineered from sustainable and natural resources. Furthermore, this book outlines possible action items that can help drive economic growth, educational opportunities, collaborative outreach, and workforce productivity to build a healthy and sustainable community. Medical technology in the industrialized world has seen rapid advancements leading to increased survival and greater patient outcomes. However, the development and implementation of these resources is not always applicable to regions in need of new and more basic ways to provide treatment. Moore’s Law, a paradigm that considers advancement synonymous with increased digitization and optimization of electronic processes, defines the history of technology. However, the functionality of advanced and “smart” technology is essentially useless in underdeveloped areas. These regions lack some of the basic requirements for innovative medical technologies to impact human health, such as electricity, access to spare parts, computer analysis tools, and network architecture. In addition, the poor physical infrastructure, insufficient management, and lack of technical culture are barriers for entry and sustainability of these technologies. Rather than importing medical devices from industrialized countries, we propose that the mindset and research focus for under developed areas must be on “successful” technologies. Simply put, these areas need technology that “gets the job done.”