Dr. Shaheen's issue of Gastrointestinal Endoscopy Clinics of North America addresses the current thinking and clinical decision making surrounding endoscopy for Barrett's Esophagus. Expert authors have contributed articles on the following topics: The Troublesome Epidemiology of Barrett’s Esophagus and Esophageal Adenocarcinoma; Who Deserves Endoscopic Screening for Esophageal Neoplasia; Alternatives to Traditional per oral Endoscopy for Screening; Effectiveness and Cost-Effectiveness of Endoscopic Screening and Surveillance; The Role of Adjunct Imaging in Endoscopic Detection of Dysplasia; Beyond Dysplasia Grade: The Role of Biomarkers in Stratifying Risk; Management of Nodular Neoplasia in Barrett’s Esophagus: Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection; EUS and Management of Superficial Esophageal Neoplasia; Radiofrequency Ablation of Barrett’s Esophagus: Patient Selection, Preparation, and Performance; Radiofrequency Ablation of Barrett’s Esophagus: Efficacy, Complications, and Durability; Cryotherapy of Barrett’s Esophagus; Care of the Post-Ablation Patient: Surveillance, Acid Suppression and Treatment of Recurrence; and Surgical Management of Superficial Esophageal Neoplasia. Readers will come away with the knowledge to diagnose and treat neoplasia and Barrett's Esophagus using the latest techniques.

Dr. Gress has assembled top experts to discuss the latest advances of using endoscopic ultrasound for diagnostic and therapeutic purposes. The issue has review articles devoted to the following topics: EUS Elastography; Contrast-Enhanced EUS; New developments in EUS- FNA Tissue Acquisition; EUS FNA: Cytologic and histologic using new techniques for interpretation; New EUS Techniques for diagnosing pancreatic neoplasms; EUS for diagnosing and treating pancreatic cysts; The role of EUS in the diagnosis of Autoimmune Pancreatitis; Therapeutic EUS for cancer treatment; and EUS-guided techniques in biliary drainage, pancreatic drainage, necrosectomy, pelvic fluid collections, hemostasis techniques, and gastrojejunostomy. The issue ends with articles that look at training issues and the future of EUS. Readers should leave with the clinical information they need to embrace the latest advances of endoscopic ultrasonography.

Endoscopic access to the small bowel has advanced significantly since the introduction of video capsule endoscopy and deep enteroscopy in early 2000. Other major advances have occurred in imaging modalities involving computed tomography and magnetic resonance studies. Due to these advances, the recent 2015 ACG guideline changed the terminology from “obscure to “small bowel bleeding because the majority of cases now can be found to have a small bowel source. The improvements in technology have advanced our ability to visualized vascular findings, inflammatory lesions, and small bowel neoplasms. Articles in this issue are devoted to these improvements in technology.

Dr. Rothstein has assembled top experts to present the current status of the role of endoscopy in managing the obese patient. Authors present current clinical information on the following topics: Small Bowel Target Devices and Techniques; Reimbursement Issues for Endoscopic Devices Used for Metabolic Endoscopy; the Physiologic Alteractions of Bariatric Surgery; Non-Balloon Gastric and Pyloric Therapies for Obesity; Aspiration Therapy for Obesity; Endoscopic Therapies after Surgery; Duodenal Mucosal Resurfacing: Role for Diabetes Treatment; Gastric Plication; and Gastric Balloons. Readers should come away with the information they need to utilize endoscopic techniques to improve outcomes in their patients.

Top expert Dr. Jacques Van Dam has compiled the most current clinical reviews on lumen-apposing stents, an important emerging field in interventional endoscopy that can substitute for more invasive surgeries. Authors have addressed the following topics in this issue: Fluid collections and pseudocysts as a complication of acute pancreatitis; Surgical management of pancreatic pseudocysts; Evolution of EUS-guided cyst gastrostomy; EUS-guided drainage of pancreatic fluid collections; EUS-guided biliary drainage as an alternative to ERCP; EUS-guided gallbladder drainage; Novel uses of LAMS; Lumen-apposing stents: Which one and why; Safety of LAMS; Endoscopic closure of fistuli; and How the experts do it: Step-by-step guide. Readers will come away with the knowledge they need to incorporate the use of LAMs in their clinical repertoire.

Eosinophilic esophagitis is an important disease that causes considerable morbidity in those afflicted. It is a major cause of esophageal symptoms, particularly dysphagia. Eosinophilic esophagitis seems to be increasing in frequency like bronchial asthma, to which it has been compared. It is complex and may have more than one pathogenesis in its varying presentations in children and adults.Dr. Katzka has invited expert authors to write clinical reviews on this complicated disease. Articles are devoted to the following topics: Pathophysiology and Definition; Incidence and Prevalence; Demographic Features; Symptoms; Endoscopic and Radiologic Findings; Children vs. Adults; Pharmacologic Treatment; Dietary Treatment; Endoscopic Treatment; and Future Directions. Readers will have the current knowledge of the endoscopic approach to diagnosis and treatment of this disease.

The field of inflammatory bowel disease has evolved in many ways. The first has been the revolution in medical therapy for the disease. With the advent of biologic therapy, the aspirational goal of therapy has become mucosal healing. These medications have also made it possible to avoid or delay surgery for ulcerative colitis and Crohn's disease. Although non-invasive strategies such as MR or CT enterography or stool-based assays are helpful, they have not been able to replace the prognostic information provided by endoscopy. Simultaneously, the quality and spectrum of tools available to perform endoscopy has widened. High resolution endoscopes are now the norm and are nearly as good as chromoendoscopy for identifying dysplasia in ulcerative colitis patients. Most gastroenterologists also perform dilations but do not generally do this for patients with IBD. Finally, newer devices such as enteroscopes, endoscopic ultrasound, and endomicroscopes are being incorporated into the algorithms to diagnose and treat complications of IBD. This issue highlights all of these advances by the experts in their fields.