Ageing and Dementia

Ageing and Dementia
Title Ageing and Dementia PDF eBook
Author Kurt Jellinger
Publisher Springer Science & Business Media
Pages 400
Release 2002-08-20
Genre Gardening
ISBN 9783211837979

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Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer's disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem. The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.

Basic Neurochemistry

Basic Neurochemistry
Title Basic Neurochemistry PDF eBook
Author George J. Siegel
Publisher Lippincott Raven
Pages 1216
Release 1999
Genre Medical
ISBN

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Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.

CNS Regeneration

CNS Regeneration
Title CNS Regeneration PDF eBook
Author Mark H. Tuszynski
Publisher Academic Press
Pages 720
Release 1999
Genre Medical
ISBN

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CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. The first comprehensive, authoritative volume on the topic of CNS regeneration Reviews current therapeutic approaches Editors and authors are experts in the field Appeals to those interested in basic science as well as those concerned with its medical application

Neurotrophic Factors

Neurotrophic Factors
Title Neurotrophic Factors PDF eBook
Author Sandra E. Loughlin
Publisher Elsevier
Pages 632
Release 2012-12-02
Genre Science
ISBN 0080571328

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This volume clearly synthesizes current information on defined neurotrophic factors, emphasizing their localization and molecular/cellular function in the central nervous system. Brain development and aging, neurodegenerative disorders, plasticity, and memory all are closely examined within the context of this rapidly expanding field. Researchers in neurobiology, cell biology, and molecular biology will find Neurotrophic Factors an invaluable reference for their research libraries. - Offers the most up-do-date synthesis of concepts on neurotrophic factors in the nervous system - Integrates molecular, cellular, and neuroanatomical concepts of neurotrophic factor function - Includes special chapters on primary, secondary, and tertiary messenger systems - Examines brain development, differentiation, neurodegenerative disorders, and adult plasticity

Translational Pain Research

Translational Pain Research
Title Translational Pain Research PDF eBook
Author Lawrence Kruger
Publisher CRC Press
Pages 458
Release 2009-11-24
Genre Health & Fitness
ISBN 1439812101

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One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide
Title The Neurobiological Basis of Suicide PDF eBook
Author Yogesh Dwivedi
Publisher CRC Press
Pages 485
Release 2012-06-25
Genre Medical
ISBN 143983881X

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With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Molecular and Cellular Therapies for Motor Neuron Diseases

Molecular and Cellular Therapies for Motor Neuron Diseases
Title Molecular and Cellular Therapies for Motor Neuron Diseases PDF eBook
Author Nicholas M Boulis
Publisher Academic Press
Pages 337
Release 2017-01-18
Genre Psychology
ISBN 0128025247

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Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig's Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. - Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases - Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance - Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy