In recent years there has been much interest in clinical pharmacology and its ap plication to the treatment of disease, including disease of the nervous system. At the same time there have been major advances in basic neuropharmacology. The aim of this book is to integrate clinical pharmacology with basic neuropharmacology and clinical neurology. The book discusses, in the light of clinical pharmacology, and par ticularly pharmacokinetics, the treatment of those disorders of the nervous system that are conventionally managed by the clinical neurologist. Matters pertaining to psychopharmacology have been deliberately excluded except in so far as they impinge on ordinary clinical neurological practice. The extent to which various disorders have been considered has depended partly on their importance to the clinical neurologist practising in non-tropical areas, and partly on the amount of data available relating to the relevant drug treatment. Thus the book is directed at clinical neurologists and those intending to practise clinical neurology. However it also contains material of in terest to the general physician, paediatrician, psychiatrist and clinical pharmacologist. Although the emphasis in this book is on drug treatment, to preserve balance it has seemed desirable to discuss briefly certain non-pharmacological aspects of thera peutics. The orderly methodical approach used in the book offers two possible advan tages: first, once the reader is familiar with the approach (see Guide to the Use of This Book, p.

Essential Neuropharmacology: The Prescriber's Guide reviews the full range of medications used by neurologists in clinical practice. Expert knowledge is given about the best use of medications in patient care. Each drug listing contains the full range of indications, their advantages and disadvantages, and tips for dosing and avoiding adverse effects. Evidence is taken from recent clinical trials, which helps the reader relate the drug descriptions to everyday clinical practice. Where appropriate, off-label uses are also described. The detailed descriptions of each medication enable the user to make quick and informed decisions with the confidence they need to serve the clinical needs of their patients effectively. The new edition is fully updated throughout. Major new additions include neuro-oncology drugs, new multiple sclerosis agents, sleep medications and new formulations. This book is an essential, user-friendly reference suitable for neurologists at all stages of their careers.

Part of the Drugs in series, this book provides an easily accessible pocket-sized guide to the use of medications when treating patients with neurological ailments. Drugs in Neurology covers the breadth of medications used in modern neurology, including each drug's indications, contra-indications, side-effects and important interactions. The underlying pharmacology also feature (where known). Practical aspects related to prescribing and therapeutic drug monitoring are covered and based on the most up-to-date evidence-based guidance. Each drug monograph contains a small section drawing on the wisdom of the senior contributors of each chapter with regards to using the medication.

* The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine

This book is a first-of-its kind reference that systematically organizes and describes the adverse effects of drugs on the nervous system. Drug safety is recognized as an important aspect of pharmaceutical companies as well as practice of medicine. Chapters include case reports of adverse effects of drugs that are published as well as reported to drug manufacturers. The book scope is broad as it covers lack of efficacy, drug resistance, drug-disease and drug-drug interactions. This information is used to improve the use of drugs as well as to design better and safer drugs for the future, and is relevant to personalized medicine in trying to match the right drugs to the patients. Drug-induced Neurological Disorders offers a unique approach to this important topic by integrating clinical neurology with pharmacology with a focus on effects of drugs on the nervous system including those used for the treatment of neurological disorders as well systemic diseases. Many adverse effects involve multiple systems of the body and the syndromes with predominant effect on the nervous system are included in this book.

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The eighth volume of this series features reviews that cover the following topics related to the treatment of a variety of CNS disorders, related diseases and basic research: - Emerging Innovative Therapies of Spinal Muscular Atrophy: Current Knowledge and Perspectives - Obesity Induced by The Neurological Drugs - Molecular Mechanism of Nervous System Disorders and Implications for New Therapeutic Targets - Glioma Imaging and Novel Agents - Screening Models for Neuroleptic Drug-Induced Hyperprolactinemia: A Mini-Review.