The zebrafish, Danio (Brachydanio) rerio, is considered one of the major model systems for the study of nervous system development and function at molecular, cellular and systems level. This is due in large part to the extensive and ongoing maturation of sophisticated genetic manipulation and mutant generation techniques. Although considerable knowledge concerning the embryonic development of the central nervous system in this animal has been gained in recent years, there is a lack of information concerning the structural organization of the adult brain. This work therefore aims at providing a neuroanatomical overview of the zebrafish brain, and identifies the major subdivisions, nuclei and tracts within the adult brain, based mainly on a comparison with the well-known brain of the closely related goldfish, Carassius auratus.

Atlas of Early Zebrafish Brain Development: A Tool for Molecular Neurogenetics, Second Edition, remains the only neuroanatomical expression atlas of important genetic and immunohistochemical markers of this vertebrate model system. It represents a key reference and interpretation matrix for analyzing expression domains of genes involved in Zebrafish brain development and neurogenesis, and serves as a continuing milestone in this research area. This updated volume provides in-situ hybridized and immunostained preparations of complete series of brain sections, revealing markers of the fundamental stages in the life history of neuronal cells in very high quality preparations and photographic plates. Specific additions to this edition include documentation on the distribution of neurons expressing GABA, dopamine and serotonin, material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon, new theories on the early organization of the telencephalon and thalamus, and integration of a comparative perspective on the mid- and hindbrain. Documentation on the distribution of neurons expressing GABA, dopamine and serotonin Material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon New theories about the early organization of the telencephalon and thalamus Integration of a comparative perspective on the mid- and hindbrain

Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic