Former NERDS teammate Heathcliff Hodges introduces a virus to Arlington, Virginia, home of the NERDS headquarters, and it transforms people into superintelligent criminal masterminds. Flinch is determined to destroy the virus, and in order to do that

Meet the NERDS, a team of eleven-year-old super spies: Duncan “Gluestick” Dewey: He’s a paste-eater who can stick to walls. Ruby “Pufferfish” Peet: Her allergies help her detect danger and dishonesty. Heathcliff “Choppers” Hodges: He controls minds with his buckteeth. Julio “Flinch” Escala: His hyperactivity gives him super speed and strength. Matilda “Wheezer” Choi: Her inhalers enable her to fly and blast enemies. Jackson “Braceface” Jones, the new recruit. This metal mouth is the team’s go-to gadget guy . . . if only he can get over becoming a NERD. Can this team of misfits save the world from their secret headquarters in the basement of their school? Can you read NERDS without laughing? Go ahead and try!

The Nerds make their return in this second installment of Buckley's series, and this time, the group must fight a villain so unlikely, he still lives with his mom. In other words, it's the Nerds against a nerd.

A virus has infected Arlington, Virginia, home of NERDS headquarters, and it’s much worse than your run-of-the-mill flu. Instead of coughing and sneezing, the victims of this voracious virus are transformed into superintelligent criminal masterminds. Soon nearly everyone—including some of the NERDS team—is plotting to take over the world. And who’s to blame for this nasty infection? None other than former NERDS teammate Heathcliff Hodges. With more people breaking out into evil cackles every day, it’s up to Flinch, the hyperactive superspy with a sweet tooth, to stop the virus. He needs to destroy the virus at its source, and to do that he’s going to have to get inside Heathcliff’s head—literally. Flinch will have to miniaturize himself and take a fantastic voyage through the supervillain’s body to fight white blood cells, stomach acid, and a nest of nasty nanobytes in the hope that he can save the world from . . . the Villain Virus.

The NERDS series combines the excitement of international espionage with the awkwardness of elementary school as it follows the adventures of a group of unpopular fifth graders who run a spy network from inside their school. With the help of cutting-edge science, they transform their nerdy qualities into incredible abilities, and the results are awesome, inspiring—and hilarious. A virus has infected Arlington, Virginia, home of NERDS headquarters, and it’s much worse than your run-of-the-mill flu. Instead of coughing and sneezing, the victims of this voracious virus are transformed into superintelligent criminal masterminds. Soon nearly everyone—including some of the NERDS team—is plotting to take over the world. And who’s to blame for this nasty infection? None other than former NERDS teammate Heathcliff Hodges. With more people breaking out into evil cackles every day, it’s up to Flinch, the hyperactive superspy with a sweet tooth, to stop the virus. He needs to destroy the virus at its source, and to do that he’s going to have to get inside Heathcliff’s head—literally. Flinch will have to miniaturize himself and take a fantastic voyage through the supervillain’s body to fight white blood cells, stomach acid, and a nest of nasty nanobytes in the hope that he can save the world from . . . the Villain Virus.

When a former member of NERDS turns into a villainous cheerleader, Matilda "Wheezer" Choi and the rest of the NERDS must infiltrate the cheerleader squad and save the world from a machine that wreaks havoc by entering other dimensions.

When a virus infects Arlington, Virginia, home of NERDS headquarters, transforming victims into criminal masterminds, it is up to Flinch to stop its spread by miniaturizing himself and entering the head of the Villain Virus's creator, Heathcliff Hodges.