Written specifically for nurses, this clinical handbook provides unmatched comprehensive information on pain management for the vulnerable neonatal population. Given the possibility of significant short- and long-term consequences of neonatal pain if left unmanaged, all nurses in neonatal settings should be familiar with the origins of neonatal pain, pain assessment, and the pharmacologic and nonpharmacologic pain management techniques outlined and explained in this clinical guide. Each chapter contains critical information on safe and proven therapies for common painful procedures, including lists of dosages and side effects. Nurses can use this clinical handbook to adopt strategies to routinely assess pain, minimize the number of painful procedures, employ drug-based and non-drug-based therapies that prevent pain in routine procedures, and eliminate pain associated with surgery. As a well-rounded guide and resource for use in neonatal settings, this portable reference also features chapters on how nurses can engage others to assist with neonatal pain, and expands upon the role of the family to ensure the best neonatal care. KEY FEATURES: The first clinical handbook specifically for nurses treating neonates A holistic, state-of-the-art resource describing pain management techniques Addresses assessment, medications, and the application of both pharmacologic and nonpharmacologic pain management techniques Lists dosages and side effects Discusses how to manage withdrawal pain from neonatal abstinence syndrome

This completely revised and updated edition offers a comprehensive overview of neonatal pain assessment and treatment. It includes the field of fetal surgery, and many other topics have been updated or added, such as circumcision analgesia, new drugs, new insights into neurophysiologic pathways of neonatal pain and new drawbacks of analgesic drugs. While in the early years of the 21st century pain treatment in neonates was still optional, it is now a tenet, and more and more institutions are looking for inspiration and good references to create their own guidelines. Written by leading researchers in the field, this book provides that inspiration and offers a valuable tool for neonatologists, anesthetists, nurses and physiotherapists. Since it also deals with prenatal and postnatal surgery, it also appeals to surgeons.

The last decade has seen major advances in the neurobiology of pain, primarily resulting from a deeper understanding of the way in which pain signals are coded and processed in the nervous system. This volume in the Molecular and Cellular Neurobiology is the first book for many years to present an integrated overview of the current state of research into the neurobiology of chronic and acute pain. While recent molecular aspects of nociception are covered in some detail, the book also emphasises the importance of viewing the pain experience as the co-ordinated response of many different areas of the nervous system. The molecular advances are set in the context of the neurobiological system of pain processing. The appropriate behavioural response to injury can therefore be thought of as the result of the integration of information processed within areas of the brain concerned with cognition, affect, sensory discrimination and movement. Chapters cover recent advances in nociceptor transduction mechanisms, nociceptor plasticity and the biochemical anatomy of pain pathways. Other contributions are concerned with the development of pain systems and with the central processing of nociceptive information studied with brain imaging techniques. Several chapters additionally cover the mechanisms of clinically important pain states such as neuropathic pain, cancer related pain and migraine. A new volume in the Molecular and Cellular Neurobiology series, this volume presents a state-of-the-art account of the neurobiological basis of pain, edited and written by the leading scientists in this field.

A practical, comprehensive guide to the special needs of infants and neonates undergoing anesthesia.

Little attention has in the past been given to physiological or pathological responses of the infant to stimuli that produce pain in older individuals. All that has changed. Drs. Anand and McGrath have joined in writing and editing this collection of chapters on many aspects of nociception and the responses within the central nervous system, behavioral responses, endocrine, cardiovascular and immune functions. The question of the benefits of some pain to communicate the presence of a potentially dangerous event is the subject of a thoughtful discussion in Chapter 4. Nociception may trigger appropriate physiological responses. However, severe responses may in themselves be deleterious as documented by the improved outlook when they are blocked during surgery. The principles and pharmacotherapy with systemic analgesic drugs (especially opioids) is given extensive and informative consideration in Chapters 5 and 6. Regional and topical anesthesia in newborn infants is thoroughly covered in Chapter 7. A welcome addition to the discussions in first chapters of the book, is the report of experienced neonatal nurses on individualized supportive care to reduce pain and stress in neonatal intensive care units. They provide a critical review of studies of behaviors of preterm and sick infants, which they augment with a description of current practices. The remaining topics that serve to broaden the perspective of those caring for infants are indicated by the chapter titles: "Moral and ethical issues in clinical practice", "Research design and research ethics", "Social and legal issues", and finally, "Future directions" by the editors.

A new edition of a highly regarded text in the series on Pain Research and Clinical Management. The book is now used as a standard reference text for those working in the field of neonatology and paediatric pain assessment and management. It provides a comprehensive resource of the latest information in the field for use by both researchers and clinicians. The text is intended for use by all professionals working in the field: neonatologists; pediatricians; anestheiologists; nurses; psychologists. Multidisciplinary editorship and authorship ensuring relevancy and balance of content for all professional groups concerned. Clinically relevant and research based. Edited and written by the best known international names in the field. Covers pain management in infants up to 1 year of age as well as term and preterm neonates. Includes new chapters on: Long-term consequences of neonatal pain from animal models; Pharmacogenetics and pharmacodynamics of analgesic drugs; Neuraxial and Regional Analgesia and Anesthesia; Fetal pain and surgery; Vulnerable Populations, Palliative Care; Infant Pain in the Home and Community, Developing Countries; Health Policy and Health Economics related to Infant Pain; Complementary and Alternative Approaches to Pain in Infancy; and Future Direction.

Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.