Over 1,000 New York-based technology startups are currently hiring. This may come as a surprise to many who thought of New York as the capital of traditional industries such as financial services, media, advertising and fashion, but not necessarily as a high-tech hub. Yet, it is true: over the past several years the level of startup activity in the city of New York has increased at an exponential rate, reaching and surpassing Boston in number of tech companies formed and money invested. It is good news for the Bloomberg administration that has made the creation of a high-tech industry a strategic priority after the financial collapse of 2008. It is also good news for the many investors in the city (both "angels" and venture capitalists) who have seen the number of opportunities created increase at a fast rate. And it is good news for the entrepreneurs who can finally benefit from a working ecosystem and from an influx of capital not seen since the internet bubble of the late '90s. "Tech and the City" is the first book telling the story of how and why this is happening: from the birth of Silicon Alley in the '90s to today's level of activity and important milestones, such as the building of the Cornell NYC Tech campus. Based on over 50 interviews with entrepreneurs, angel investors, venture capitalists, university professors, members of the Bloomberg administration and other stakeholders, this book's objective is to inform and inspire the current generation of entrepreneurs. Fred Wilson, the best known venture capitalists in New York and one of the most important in the US, wrote in his foreword: "I hope this book will be an inspiration to New Yorkers to embrace the technology revolution that has taken hold in our city. I also hope it will be an inspiration to other cities, countries, and cultures who may have missed out on the initial wave of the technology revolution." "Tech and the City" takes us on a historical and geographical tour of New York, while addressing the hot themes for entrepreneurs and investors. It is also a guide to help navigate the NYC community: how to network and become part of the community; what to read to understand and keep informed; where to raise capital; what help is available for any professional, entrepreneur, student, researcher seeking to settle in the city. And this is just the basis for an ongoing conversation, which we hope will continue on our blog, http: //www.tech-and-the-city.com The authors, Alessandro Piol and Maria Teresa Cometto, know the story and the industry well. Alessandro has been a New Yorker for 35 years and a venture capitalist for 20, during which he has seen firsthand the evolution of the New York entrepreneurial ecosystem. He has a deep knowledge of the tech industry and a passionate involvement in the NYC community, where he invests in, and mentors, a number of young entrepreneurs. Maria Teresa Cometto is a journalist and award-winning author based in New York since 2000, covering business and high-tech for the largest Italian daily, Corriere della Sera, and for other important publications.

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The pharmaceutical industry is almost boundless in its ability to supply new drug therapies, but how does one decide which are the best medicines to use within restricted budgets? With particular emphasis on modeling, methodologies, data sources, and application to real-world dilemmas, Pharmacoeconomics: From Theory to Practice provides an introduc

Braithwaite's argument against punitive justice systems and for restorative justice systems establishes that there are good theoretical and empirical grounds for anticipating that well designed restorative justice processes will restore victims, offenders, and communities better than existing criminal justice practices. Counterintuitively, he also shows that a restorative justice system may deter, incapacitate, and rehabilitate more effectively than a punitive system. This is particularly true when the restorative justice system is embedded in a responsive regulatory framework that opts for deterrence only after restoration repeatedly fails, and incapacitation only after escalated deterrence fails. Braithwaite's empirical research demonstrates that active deterrence under the dynamic regulatory pyramid that is a hallmark of the restorative justice system he supports, is far more effective than the passive deterrence that is notable in the stricter "sentencing grid" of current criminal justice systems.

What happens when the bottlenecks that stand between supply and demand in our culture go away and everything becomes available to everyone? "The Long Tail" is a powerful new force in our economy: the rise of the niche. As the cost of reaching consumers drops dramatically, our markets are shifting from a one-size-fits-all model of mass appeal to one of unlimited variety for unique tastes. From supermarket shelves to advertising agencies, the ability to offer vast choice is changing everything, and causing us to rethink where our markets lie and how to get to them. Unlimited selection is revealing truths about what consumers want and how they want to get it, from DVDs at Netflix to songs on iTunes to advertising on Google. However, this is not just a virtue of online marketplaces; it is an example of an entirely new economic model for business, one that is just beginning to show its power. After a century of obsessing over the few products at the head of the demand curve, the new economics of distribution allow us to turn our focus to the many more products in the tail, which collectively can create a new market as big as the one we already know. The Long Tail is really about the economics of abundance. New efficiencies in distribution, manufacturing, and marketing are essentially resetting the definition of what's commercially viable across the board. If the 20th century was about hits, the 21st will be equally about niches.

Missing data pose challenges to real-life data analysis. Simple ad-hoc fixes, like deletion or mean imputation, only work under highly restrictive conditions, which are often not met in practice. Multiple imputation replaces each missing value by multiple plausible values. The variability between these replacements reflects our ignorance of the true (but missing) value. Each of the completed data set is then analyzed by standard methods, and the results are pooled to obtain unbiased estimates with correct confidence intervals. Multiple imputation is a general approach that also inspires novel solutions to old problems by reformulating the task at hand as a missing-data problem. This is the second edition of a popular book on multiple imputation, focused on explaining the application of methods through detailed worked examples using the MICE package as developed by the author. This new edition incorporates the recent developments in this fast-moving field. This class-tested book avoids mathematical and technical details as much as possible: formulas are accompanied by verbal statements that explain the formula in accessible terms. The book sharpens the reader’s intuition on how to think about missing data, and provides all the tools needed to execute a well-grounded quantitative analysis in the presence of missing data.