This volume provides a comprehensive and state-of-the-art text for health care professionals who are interested in the diagnosis and treatment of nausea and vomiting. Because the majority of causes of nausea and vomiting arise from disorders of the gastrointestinal system, the text emphasizes the GI system by organ from esophagus to colon. It also reviews how disorders of the abdominal wall, the endocrine system, and autonomic and central nervous systems can contribute to nausea and vomiting syndromes that can be difficult to diagnose. Various treatment modalities are presented and organized in terms of drug treatments, electrical stimulation devices, and dietary therapy and nutritional support. Furthermore, the book is enhanced by chapters on the pathophysiology of nausea, the pathophysiology of vomiting, the physiological changes in the brain during nausea and vomiting, and the psychological underpinnings of nausea and vomiting. And because many children are afflicted with unexplained nausea and vomiting, a chapter devoted to pediatric patients is also included. Written by authorities in the field, Nausea and Vomiting: Diagnosis and Treatment is a valuable resource that will help practitioners and healthcare providers consider specific diagnoses in treating the noxious and burdensome symptoms of nausea and vomiting.

This study helps clinicians to better understand the relationship of nausea and vomiting to various clinical diseases and disorders, and to treat these symptoms more effectively. It is a practical reference to current medical opinion, providing guidelines to improve clinicial decision-making.

The following papers were presented at an international symposium on the mechanisms and treatment of nausea and vomiting in man held in Oxford in 1984. I believe that this meeting was the first occasion on which representatives from such a wide variety of scientific and clinical specialities had come together to review and debate the spectrum of the vomiting phenomenon. An attempt was made to put before an invited international audience all the pertinent facts on the different facets of the topic and then to encourage extensive discussion of the contentious issues. The first day of the meeting was devoted to the basic science ap proach to the problem and the second day to the more clinical aspects. This format has been broadly retained in the layout of the book, with the addition of summary chapters reviewing each day's contributions and focusing upon areas of particular importance. Acknowledgement must here be made to the enormous input from the many participants who either spoke in the debate or rose and themselves gave small presenta tions in addition to those of the invited speakers. The meeting occurred at a time of increasing interest in the problem of nausea and vomiting, especially because of its importance in cancer chemotherapy and radiation therapy, and even in space travel.

A practical resource providing guidance on treatment options and management strategies for postoperative nausea and vomiting.

Treatment tolerance is a challenge for most cancer patients, and it is therefore essential that healthcare professionals (HCPs) are quick to recognize adverse events and implement management strategies to address them. Prevention of Nausea and Vomiting in Cancer Patients provides comprehensive guidance on managing nausea and vomiting, which are common and often severe adverse events experienced by patients receiving chemotherapy and radiotherapy. The book refers to the latest American Society of Clinical Oncology (ASCO), European Society of Medical Oncology (ESMO), and Multinational Association for Supportive Care in Cancer (MASCC) guidelines and will be a useful resource for oncologists, oncology fellows, general physicians, and other HCPs wishing to learn more about the effective management of chemotherapy-and radiotherapy-induced nausea and vomiting in cancer patients.

Nausea is a complex sensation that results from the interaction of certain fixed biological factors, such as gender, with changeable psychological factors, such as anxiety. This is the first book to provide a complete, in-depth explanation of what we know about nausea, along with the latest research results on its causes and treatment. As it is the product of long-term collaboration between scientists from the three main approaches to studying and treating nausea--psychology, gastroenterology, and physiology--the information this book provides is both comprehensive and well integrated. The book is divided into two parts, on mechanisms and management, respectively, and four sections. The chapters in Section I introduce the concept of nausea as a protective control mechanism with individual dynamic thresholds, explain the function of nausea, review past and present conceptions of nausea, and describe the prevalence of nausea in different conditions.Section II includes four basic chapters that review what is known about the physiological bases of nausea. Other chapters explore the roles of the central nervous system, autonomic nervous system, endocrine system, and gastric dysrhythmias. Section III presents the difficult problem of measuring nausea, with chapters focusing on measuring nausea in humans and studying it in animals.Section IV forms the second part of the book, on the management of nausea. The main chapters cover nausea and its treatment in several conditions, including chronic nausea, diabetes, pregnancy, post-operative, cancer and its treatment, and provocative motion. A final chapter discusses future research, including three preliminary studies of novel treatment approaches.

This fourth edition of Autonomic Failure (now available in paperback) covers the many recent advances made in our understanding of the autonomic nervous system. There are 20 new chapters and extensive revisions of all other contributions. Autonomic failure, fourth edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. This new edition continues to provide practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine, with a rational guide to aid in the recognition and management of autonomic disorders. The book starts with an updated classification of autonomic disorders and a history of the autonomic nervous system. The first two sections of the book deal with the fundamental aspects of autonomic structure, function, and integration. There are new chapters dealing with neurobiology, nerve growth factors, genetic mutations, neural and hormonal control of the cerebral circulation, innervation of the lung, and pathophysiological mechanisms causing nausea and vomiting. Advances in the clinical management of autonomic disorders are critically dependent on the bridge made between the basic and applied sciences.