A wide-ranging history of rickets tracks the disease’s emergence, evolution, and eventual treatment—and exposes the backstory behind contemporary worries about vitamin D deficiency. Rickets, a childhood disorder that causes soft and misshapen bones, transformed from an ancient but infrequent threat to a common scourge during the Industrial Revolution. Factories, mills, and urban growth transformed the landscape. Malnutrition and insufficient exposure to sunlight led to severe cases of rickets across Europe and the United States, affecting children in a variety of settings: dim British cities and American slave labor camps, moneyed households and impoverished ones. By the late 1800s, it was one of the most common pediatric diseases, seemingly an intractable consequence of modern life. Starved for Light offers the first comprehensive history of this disorder. Tracing the efforts to understand, prevent, and treat rickets—first with the traditional remedy of cod liver oil, then with the application of a breakthrough corrective, industrially produced vitamin D supplements—Christian Warren places the disease at the center of a riveting medical history, one alert to the ways society shapes our views on illness. Warren shows how physicians and public health advocates in the United States turned their attention to rickets among urban immigrants, both African Americans and southern Europeans; some concluded that the disease was linked to race, while others blamed poverty, sunless buildings and cities, or cultural preferences in diet and clothing. Spotlighting rickets’ role in a series of medical developments, Warren leads readers through the encroachment on midwifery by male obstetricians, the development of pediatric orthopedic devices and surgeries, early twentieth-century research into vitamin D, appalling clinical experiments on young children testing its potential, and the eventual commercialization of all manner of vitamin D supplements. As vitamin D consumption rose in the mid-twentieth century, rickets—previously a major concern for doctors, parents, and public health institutions—faded in its severity and frequency, and as a topic of discussion. But despite the availability of drugstore supplements and fortified milk, small numbers of cases still appear today, and concerns and controversies about vitamin D deficiency in general continue to grow. Sweeping and engaging, Starved for Light illuminates the social conditions underpinning our cures and our choices, helping us to see history’s echoes in contemporary prescriptions.

Formerly the Handbook of Behavior Problems of the Dog and Cat, the new edition of the definitive guide to the diagnosis and treatment of behavior problems of the dog and cat has been extensively updated. It retains the highly practical approach that has proved so successful in previous editions, offering diagnostic guidelines, preventative advice, treatment guidelines and charts, case examples, client forms and handouts, and product and resource suggestions along with details on the use of drugs and natural supplements to help optimize the behavior services offered in practice. To add to these features, the third edition is now fully referenced, there is significant new content, the book as been written with the entire hospital team in mind, and many color images have been added. The new edition welcomes a wide international mix of new contributors from Australia, Spain, Mexico and the United States. A website link gives access to the handouts and forms previously found on disk. As well as fulfilling its original purpose as a practical tool for the busy clinician, this edition offers valuable and useful support material for all those studying the field of companion animal behavior. Now in full color and using a revised format, Behavior Problems of the Dog and Cat remains the most complete, up-to-date and practical resource for the treating and diagnosing canine and feline behavior problems. Many hot new topics covered including stress and its effects on health and behavior, and pain assessment and management. Three chapters are added, dealing with canine and feline communication, how to distinguish behavioral versus medical problems, and how to deal with fear and aggression in the clinic. Now thoroughly referenced to the scientific literature. Includes updates on drugs and natural therapeutics. Pain assessment charts now included. All-new color format offers extra illustrations throughout.

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.