If it walks like a dragon shifter and it talks like a dragon shifter. . . but it can’t shift? What then? The entire country rejoiced when, out of a golden egg, Roxana Goldenscales hatched. It’s not every day (or even every decade) that a dragona princess graces the earth with her presence. But like most rare, valuable, and defenseless things, every moment of Roxana’s existence is supervised, planned, and observed. Or at least, they were. Until she ran away. Her decision to flee from her gilded pedestal wasn’t an easy one, and nothing’s gone quite right since. Her love life’s confusing, her closet’s cramped (and a little smelly), and her useless, ornamental dragon scales itch constantly. But after finding a group of misfit friends who support her, Roxana’s making a life for herself—one that she chooses. As usual, the rest of the world has other ideas. The Manhattan werewolves, the demon-spawn leaders, and Roxana’s powerful parents all want her to go back home double quick. Can a helpless princess find the strength to stand on her own? Or will the danger for her friends be so steep that she’s swept right back into the very cage she fled? KW: magical realism, fantasy comedy, comedic fantasy, light and fun fantasy, comedy fantasy, magical romantic comedy, fantasy romantic comedy, fantasy that's funny, fantasy to make you laugh, urban fantasy, contemporary fantasy, funny urban fantasy, funny contemporary fantasy, fantasy romance, fantasy romance book, comedy book, funny book, funny fantasy book series.

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.

Find relief from chronic itch in this comprehensive guide. We have all experienced itch, whether from insect bites or dry skin, but millions of people worldwide have chronic or even intractable itch. Just like chronic pain, chronic itch interferes with a person’s ability to function—and even affects quality of life. Living with Itch offers relief, drawing on the authors’ vast knowledge of itch, the suffering it causes, and available treatments. Itch researchers and clinicians Drs. Gil Yosipovitch and Shawn G. Kwatra explain the cascade of physiological events that causes us to experience itch. They describe the many skin diseases, from atopic dermatitis (eczema) to psoriasis, and conditions like chronic kidney disease, lymphoma, HIV, and neuropathies that cause itch. Living with Itch provides information on preventing itch as well as topical and systemic ways to treat it. Patient and parent narratives illustrate how people cope with itch and how, with medical and social support, itch can be managed.

The Institute of Medicine's (IOM's) Roundtable on Research and Development of Drugs, Biologics, and Medical Devices evolved from the Forum on Drug Development, which was established in 1986. Sponsor representatives and IOM determined the importance of maintaining a neutral setting for discussions regarding long-term and politically sensitive issues justified the need to revise and enhance past efforts. The new Roundtable is intended to be a mechanism by which a broad group of experts from the public* and private sectors can be convened to conduct a dialogue and exchange information related to the development of drugs, biologics, and medical devices. Members have expertise in clinical medicine, pediatrics, clinical pharmacology, health policy, health insurance, industrial management, and product development; and they represent interests that address all facets of public policy issues. From time to time, the Roundtable requests that a workshop be conducted for the purpose of exploring a specific topic in detail and obtaining the views of additional experts. The first workshop for the Roundtable was held on April 14 and 15, 1998, and was entitled Assuring Data Quality and Validity in Clinical Trials for Regulatory Decision Making. The summary on that workshop is available from IOM. This workshop summary covers the second workshop, which was held on May 24 and 25, 1999, and which was aimed at facilitating the development and proper use of drugs, biologics, and medical devices for infants and children. It explores the scientific underpinnings and clinical needs, as well as the regulatory, legal, and ethical issues, raised by this area of research and development.

A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: "... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes...." Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout.

A great book providing essential information for the accurate diagnosis and treatment of dermatologic diseases. The text opens with a discussion of the basic function and structure of the skin, a description of lesions, and instructions on how to perform a biopsy; follows with a section on the principles of dermatologic therapy, and a section on individual dermatologic disorders; and concludes with a section explaining when the primary care physician should refer a patient to a specialist. Features numerous tables and figures to enhance understanding.

When the first edition of this pioneering text was published, only a few dermatologists were trained to utilize the dermatoscope for the diagnosis and follow-up of hair diseases. The technique is now more popular worldwide, prompting the development of this updated second edition, which now includes a section devoted entirely to nail dermoscopy and