Disclosure statement: Topic Editor Prof. Silvia Salinas Blemker is a Co-founder and Vice President of Springbok, Inc. Charlottesville, VA. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

The term "neuromechanics" defines an integrative approach that combines the neuromuscular control and the biomechanical aspects of physical behavior in humans and animals. Crucial to this approach is a detailed description and modeling of the interaction between the nervous system and the controlled biomechanical plant. Only then do we have the broader context within which to understand evolution, movement mechanics, neural control, energetics, disability and rehabilitation. In addition to enabling new basic science directions, understanding the interrelations between movement neural and mechanical function should also be leveraged for the development of personalized wearable technologies to augment or restore the motor capabilities of healthy or impaired individuals. Similarly, this understanding will empower us to revisit current approaches to the design and control of robotic and humanoid systems to produce truly versatile human-like physical behavior and adaptation in real-world environments. This Research Topic is therefore poised at an opportune moment to promote understanding of apparently disparate topics into a coherent focus.

Neurotransmitters, Drugs and Brain Function aims to link basic aspects of the activity of neurotransmitters at the receptor and synaptic level with their role in normal brain function, disease states, and drug action. Thus, the material considers to what extent our knowledge of the central synaptic action of certain drugs can explain their possible roles in the cause of diseases and in the modes of action of drugs effective in those conditions. It offers a working explanation of drug and neurotransmitter action in CNS function, with a clear, comprehensive, and challenging style of writing. The authors review the chemical basis for drugs and the conditions they treat. It also, includes numerous illustrations and schematic diagrams.

Bioinspired Legged Locomotion: Models, Concepts, Control and Applications explores the universe of legged robots, bringing in perspectives from engineering, biology, motion science, and medicine to provide a comprehensive overview of the field. With comprehensive coverage, each chapter brings outlines, and an abstract, introduction, new developments, and a summary. Beginning with bio-inspired locomotion concepts, the book's editors present a thorough review of current literature that is followed by a more detailed view of bouncing, swinging, and balancing, the three fundamental sub functions of locomotion. This part is closed with a presentation of conceptual models for locomotion. Next, the book explores bio-inspired body design, discussing the concepts of motion control, stability, efficiency, and robustness. The morphology of legged robots follows this discussion, including biped and quadruped designs. Finally, a section on high-level control and applications discusses neuromuscular models, closing the book with examples of applications and discussions of performance, efficiency, and robustness. At the end, the editors share their perspective on the future directions of each area, presenting state-of-the-art knowledge on the subject using a structured and consistent approach that will help researchers in both academia and industry formulate a better understanding of bioinspired legged robotic locomotion and quickly apply the concepts in research or products. Presents state-of-the-art control approaches with biological relevance Provides a thorough understanding of the principles of organization of biological locomotion Teaches the organization of complex systems based on low-dimensional motion concepts/control Acts as a guideline reference for future robots/assistive devices with legged architecture Includes a selective bibliography on the most relevant published articles

Vascular dementia is one of the most common forms of mental deterioration for the elderly, second only to Alzheimer's disease. It should not be defined as a single disease, but rather as a group of syndromes that relate to different vascular mechanisms. This is one of the first books to be solely dedicated to the specific class of vascular dementia known as subcortical vascular dementia. The strict focus of the chapters give an depth review that will clarify many different aspects and give an unprecedented amount of detail about this clinical problem. Considering that vascular dementia can be prevented with early diagnosis, the research presented in this book will be important for both students and specialists of this important field.

Fully updated throughout, this popular book explains the history, rationale, and detailed descriptions of the class of soft tissue manipulation methods known collectively as NMT techniques. Complete with accompanying website - www.chaitowonline.com - which contains film sequences of the author demonstrating the techniques, this book will be ideal for bodyworkers and acupuncturists in Europe, the USA and beyond. Facilitates the rapid and accurate identification of local soft-tissue dysfunction Explains the origin of soft tissue distress Provides diverse maps and explanations for the patterns of tender and trigger points seen daily in clinical practice Includes guidance on the use of NMT for the treatment of the symptoms of fibromyalgia and abdominal dysfunction Gives important guidance on the treatment of trigger points in treating lymphatic dysfunction Discusses the use of NMT in the management of pain and hyperventilation Explains the diagnostic and therapeutic value of tender reflex points related to viscero-somatic and somatic-visceral reflexes Describes both European and North American versions of NMT Provides a clear set of treatment options for all bodywork therapists and acupuncture practitioners Authored by a highly respected, internationally known teacher, practitioner and author, with contributions from three leading practitioners from the U.S. and Europe Contains a new chapter on the value of Thai Yoga massage, associated with NMT methodology Contains source material and commentary on the contribution of Raymond Nimmo DC in the evolution of NMT Website - www.chaitowonline.com - containing updated video clips demonstrating the application of NMT