Muscle Homeostasis and Regeneration

Muscle Homeostasis and Regeneration
Title Muscle Homeostasis and Regeneration PDF eBook
Author Antonio Musarò
Publisher MDPI
Pages 500
Release 2020-11-20
Genre Science
ISBN 3039434365

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The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.

Anatomy and Physiology

Anatomy and Physiology
Title Anatomy and Physiology PDF eBook
Author J. Gordon Betts
Publisher
Pages 0
Release 2013-04-25
Genre
ISBN 9781947172807

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Anatomy & Physiology

Anatomy & Physiology
Title Anatomy & Physiology PDF eBook
Author Lindsay Biga
Publisher
Pages
Release 2019-09-26
Genre
ISBN 9781955101158

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A version of the OpenStax text

Frontiers in Skeletal Muscle Wasting, Regeneration and Stem Cells

Frontiers in Skeletal Muscle Wasting, Regeneration and Stem Cells
Title Frontiers in Skeletal Muscle Wasting, Regeneration and Stem Cells PDF eBook
Author Carlos Hermano J. Pinheiro
Publisher Frontiers Media SA
Pages 261
Release 2016-05-25
Genre Physiology
ISBN 2889198324

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The search for knowledge on cellular and molecular mechanisms involved in skeletal muscle mass homeostasis and regeneration is an exciting scientific area and extremely important to develop therapeutic strategies for neuromuscular disorders and conditions related to muscle wasting. The mechanisms involved in the regulation of skeletal muscle mass and regeneration consist of molecular signaling pathways modulating protein synthesis and degradation, bioenergetics alterations and preserved function of muscle stem cells. In the last years, different kinds of stem cells has been reported to be localized into skeletal muscle (satellite cells, mesoangioblasts, progenitor interstitial cells and others) or migrate from non-muscle sites, such as bone marrow, to muscle tissue in response to injury. In addition, myogenic progenitor cells are also activated in skeletal muscle wasting disorders. The goal of this research topic is to highlight the available knowledge regarding skeletal muscle and stem cell biology in the context of both physiological and pathological conditions. Our purpose herein is to facilitate better dissemination of research into skeletal muscle physiology field. Frontiers in Physiology is a journal indexed in: PubMed Central, Scopus, Google Scholar, DOAJ, CrossRef.

Muscle Atrophy

Muscle Atrophy
Title Muscle Atrophy PDF eBook
Author Junjie Xiao
Publisher Springer
Pages 618
Release 2018-11-02
Genre Science
ISBN 9811314357

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The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology.

Skeletal Muscle Repair and Regeneration

Skeletal Muscle Repair and Regeneration
Title Skeletal Muscle Repair and Regeneration PDF eBook
Author Stefano Schiaffino
Publisher Springer Science & Business Media
Pages 385
Release 2008-01-18
Genre Medical
ISBN 1402067682

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Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. It provides up-to-date coverage and presents a broad range of topics.

Planarian Regeneration

Planarian Regeneration
Title Planarian Regeneration PDF eBook
Author Jochen C. Rink
Publisher Humana
Pages 0
Release 2018-06-19
Genre Science
ISBN 9781493978007

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This volume explores the various facets of planaria as a biomedical model system and discusses techniques used to study the fascinating biology of these animals. The chapters in this book are divided into two parts: Part One looks at the biodiversity of planarian species, the molecular orchestration of regeneration, ecology of planarians in their natural habitats and their history as lab models. Part Two talks about experimental protocols for studying planarians, ranging from the establishment of a planarian research colony, to RNA and DNA extraction techniques, all the way to single stem cell transplantations or metabolomics analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Planarian Regeneration: Methods and Protocols is a valuable resource for both newcomers to the field and experts within established planarian laboratories.