Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research. - Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions - Descibes the technologies that have contributed to our current knowledge about the Flaviviruses - Identifies the major problems faced in understanding the virus-host interactins that result in disease - An exhaustive compendium of current and past knowledge on the Flavivirus family

Japanese Encephalitis (JE), a mosquito borne disease, is the leading cause of viral encephalitis in 14 Asian countries due to its epidemic potential, high case fatality rate and increased possibility of lifelong disability in patients who recover from this dreadful disease. In spite of seriousness of the disease, still only few books are available for ready reference. Hence, this book will be useful for students, entomologists, paramedical staff and vector control managers in public health. The objective of the book is to disseminate the knowledge gained by the author from ecological studies on JE vectors undertaken in 2 endemic and 2 non endemic areas of Northern India over a period of last 15 years (1998-2012) of research in the field of ecology of mosquito vectors of JE virus initially at National Institute of Communicable Diseases (Ministry of Health & Family Welfare, Government of India), Delhi and later at Jamia Millia Islamia, a Central University, Delhi, to anyone who wishes to curtail death of children due to this dreaded disease. Of the thousand suspected JE deaths in India annually, more than 75% is contributed by Northern India wherein disease transmission failed to be explained based on entomological evidence due to inadequate mosquito surveillance tool used in determining JE vector density. In order to overcome the above problem, Dr Bina Pani Das, the author of this book, developed “BPD hop cage method”, a simple, cost effective, and operationally feasible surveillance tool specially designed to capture predominantly day resting adult Cx. tritaeniorhynchus mosquitoes, the principal JE vector species in the country from land and aquatic vegetation.

Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses. The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.

Offering up-to-date coverage of familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease, as well as viruses that are almost unknown in most developed nations, Zika and Other Neglected and Emerging Flaviviruses brings together information that allows for easy comparison of similarities and differences of this viral group in a single, convenient volume. Each chapter includes a brief Introduction, history, the diseases, the virus, the immune response, prevention or treatment, an extensive list of references, and a summary overview. The book concludes with a chapter tying together information about flaviviruses and other potential new microbial threats. - Covers familiar flaviviruses that are spreading into new regions or are causing increasingly severe disease (such as Zika, dengue and West Nile viruses), as well as lesser-knowns viruses such as tick-borne encephalitis virus, Powassan virus, Omsk hemorrhagic fever, and Murray Valley encephalitis virus. - Allows health-related personnel to search for potential treatments and protective responses by examining what measure did or did not work with other, related flaviviruses. - Helps readers understand how to prevent or contain newly emerging viral threats—a particularly timely topic regarding the global spread of COVID-19 and the potential of tick-borne encephalitis to rapidly spread and cause severe illness, panic, and disruption of economies. - Consolidates today's available information on this timely topic into a single, convenient resource.

Since the dawn of medical science, people have recognized connections between a change in the weather and the appearance of epidemic disease. With today's technology, some hope that it will be possible to build models for predicting the emergence and spread of many infectious diseases based on climate and weather forecasts. However, separating the effects of climate from other effects presents a tremendous scientific challenge. Can we use climate and weather forecasts to predict infectious disease outbreaks? Can the field of public health advance from "surveillance and response" to "prediction and prevention?" And perhaps the most important question of all: Can we predict how global warming will affect the emergence and transmission of infectious disease agents around the world? Under the Weather evaluates our current understanding of the linkages among climate, ecosystems, and infectious disease; it then goes a step further and outlines the research needed to improve our understanding of these linkages. The book also examines the potential for using climate forecasts and ecological observations to help predict infectious disease outbreaks, identifies the necessary components for an epidemic early warning system, and reviews lessons learned from the use of climate forecasts in other realms of human activity.

New emerging diseases, new diagnostic modalities for resource-poor settings, new vaccine schedules ... all significant, recent developments in the fast-changing field of tropical medicine. Hunter's Tropical Medicine and Emerging Infectious Diseases, 10th Edition, keeps you up to date with everything from infectious diseases and environmental issues through poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies that result from traveling to tropical or subtropical regions. This comprehensive resource provides authoritative clinical guidance, useful statistics, and chapters covering organs, skills, and services, as well as traditional pathogen-based content. You'll get a full understanding of how to recognize and treat these unique health issues, no matter how widespread or difficult to control. - Includes important updates on malaria, leishmaniasis, tuberculosis and HIV, as well as coverage of Ebola, Zika virus, Chikungunya, and other emerging pathogens. - Provides new vaccine schedules and information on implementation. - Features five all-new chapters: Neglected Tropical Diseases: Public Health Control Programs and Mass Drug Administration; Health System and Health Care Delivery; Zika; Medical Entomology; and Vector Control – as well as 250 new images throughout. - Presents the common characteristics and methods of transmission for each tropical disease, as well as the applicable diagnosis, treatment, control, and disease prevention techniques. - Contains skills-based chapters such as dentistry, neonatal pediatrics and ICMI, and surgery in the tropics, and service-based chapters such as transfusion in resource-poor settings, microbiology, and imaging. - Discusses maladies such as delusional parasitosis that are often seen in returning travelers, including those making international adoptions, transplant patients, medical tourists, and more. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.