Generally, spontaneous pattern formation phenomena are random and repetitive, whereas elaborate devices are the deterministic product of human design. Yet, biological organisms and collective insect constructions are exceptional examples of complex systems that are both self-organized and architectural. This book is the first initiative of its kind toward establishing a new field of research, Morphogenetic Engineering, to explore the modeling and implementation of “self-architecturing” systems. Particular emphasis is placed on the programmability and computational abilities of self-organization, properties that are often underappreciated in complex systems science—while, conversely, the benefits of self-organization are often underappreciated in engineering methodologies. Altogether, the aim of this work is to provide a framework for and examples of a larger class of “self-architecturing” systems, while addressing fundamental questions such as br” How do biological organisms carry out morphogenetic tasks so reliably? br” Can we extrapolate their self-formation capabilities to engineered systems?br” Can physical systems be endowed with information (or informational systems be embedded in physics) so as to create autonomous morphologies and functions?br” What are the core principles and best practices for the design and engineering of such morphogenetic systems?

This book provides a basic yet unified overview of theory and methodologies for evolutionary developmental systems. Based on the author’s extensive research into the synergies between various approaches to artificial intelligence including evolutionary computation, artificial neural networks, and systems biology, it also examines the inherent links between biological intelligence and artificial intelligence. The book begins with an introduction to computational algorithms used to understand and simulate biological evolution and development, including evolutionary algorithms, gene regulatory network models, multi-cellular models for neural and morphological development, and computational models of neural plasticity. Chap. 2 discusses important properties of biological gene regulatory systems, including network motifs, network connectivity, robustness and evolvability. Going a step further, Chap. 3 presents methods for synthesizing regulatory motifs from scratch and creating more complex regulatory dynamics by combining basic regulatory motifs using evolutionary algorithms. Multi-cellular growth models, which can be used to simulate either neural or morphological development, are presented in Chapters 4 and 5. Chap. 6 examines the synergies and coupling between neural and morphological evolution and development. In turn, Chap. 7 provides preliminary yet promising examples of how evolutionary developmental systems can help in self-organized pattern generation, referred to as morphogenetic self-organization, highlighting the great potentials of evolutionary developmental systems. Finally, Chap. 8 rounds out the book, stressing the importance and promise of the evolutionary developmental approach to artificial intelligence. Featuring a wealth of diagrams, graphs and charts to aid in comprehension, this book offers a valuable asset for graduate students, researchers and practitioners who are interested in pursuing a different approach to artificial intelligence.

This book constitutes the refereed post-conference proceedings of the 21st Annual Simulation Technology and Training Conference, SimTecT 2016, and the 47th International Simulation and Gaming Association Conference, ISAGA 2016, Held as Part of the First Australasian Simulation Congress, ASC 2016, held in Melbourne, VIC, Australia, in September 2016. The 28 revised full papers included in the volume were carefully reviewed and selected from 55 submissions. They are organized in the following topical sections: Making the grade; Come to think of it; From here to fidelity; The name of the game; and Ahead of the game.

Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the fi

Over the last century, medicine has come out of the "black bag" and emerged as one of the most dynamic and advanced fields of development in science and technology. Today, biomedical engineering plays a critical role in patient diagnosis, care, and rehabilitation. As such, the field encompasses a wide range of disciplines, from biology and physiology to material science and nanotechnology. Reflecting the enormous growth and change in biomedical engineering during the infancy of the 21st century, The Biomedical Engineering Handbook enters its third edition as a set of three carefully focused and conveniently organized books. Reviewing applications at the leading edge of modern biomedical engineering, Tissue Engineering and Artificial Organs explores transport phenomena, biomimetics systems, biotechnology, prostheses, artificial organs, and ethical issues. The book features approximately 90% new material in the tissue engineering section, integrates coverage of life sciences with a new section on molecular biology, and includes a new section on bionanotechnology. Prominent leaders from around the world share their expertise in their respective fields with many new and updated chapters. New technologies and methods spawned by biomedical engineering have the potential to improve the quality of life for everyone, and Tissue Engineering and Artificial Organs sheds light on the tools that will enable these advances.

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine. More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics.

Through expanded intelligence, the use of robotics has fundamentally transformed a variety of fields, including manufacturing, aerospace, medical, social services, and agriculture. Providing successful techniques in robotic design allows for increased autonomous mobility, which leads to a greater productivity level. Novel Design and Applications of Robotics Technologies provides innovative insights into the state-of-the-art technologies in the design and development of robotic technologies and their real-world applications. The content within this publication represents the work of interactive learning, microrobot swarms, and service robots. It is a vital reference source for computer engineers, robotic developers, IT professionals, academicians, and researchers seeking coverage on topics centered on the application of robotics to perform tasks in various disciplines.