This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives

This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives

Molecular Imprinted Polymer Composites: Synthesis, Characterisation and Applications covers the design of composite materials containing nanostructures and molecular imprinted polymers that has materialized the ever-sought out vision of homogeneous molecular imprinted polymers. The inherent high surface-to-volume ratio of nanostructures has served well in increasing the surface area of conventional bulk polymers. In recent decades, molecularly imprinted polymer nanocomposite materials have attracted much attention for their potential applications in the fields of separation science, sensing, drug delivery, waste water treatment and catalysis, hence this book provides a much needed update on progress. - Includes information on molecular imprinted polymer composites and their potential for commercialization - Discusses their synthesis, characterization and applications - Analyzes the effect of incorporation of different nanostructures on the thermodynamic, kinetic and adsorption behavior of imprinted sorbents

Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

This handbook provides a useful guide to preparing molecularly imprinted polymers (MIPs) for diverse practical applications. The first chapter covers the general aspects of molecular imprinting technology. The following chapters focus on specific applications, such as MIPs for sample concentration, MIPs for chromatography and related techniques, MIPs as sensor components, MIPs as traps for medical and bioremediation, MIPs as catalysts and artificial enzymes, and MIPs as components of drug delivery systems. All chapters of the handbook follow a common structure: interest of the MIP approach for that application specific aspects of the synthesis of MIPs for this aim (requirements and general recipes) representative examples of MIPs and their performance for that application a look to the future.

Molecularly Imprinted Polymers (MIPs): Commercialization Prospects guides the reader through the various steps in the conceptualization, design, preparation and innovative applications of molecularly imprinted polymers while also demystifying the challenges relating to commercialization. Sections cover molecularly imprinted polymers, design, modeling, compositions and material selection. Other sections describe novel methods and discuss the challenges relating to the use of molecularly imprinted polymers in specific application areas. The final chapters of the book explore the current situation in terms of patents and commercialized materials based on MIPs, as well as prospects and possible opportunities. This is a valuable resource for all those with an interest in the development, application, and commercialization of molecularly imprinted polymers, including researchers and advanced students in polymer science, polymer chemistry, nanotechnology, materials science, chemical engineering, and biomedicine, as well as engineers, scientists and R&D professionals with an interest in MIPs for advanced applications. - Covers all stages of molecular imprinting, from conceptualization, modeling, and solvent choice, to extraction, monomer composition and miniaturization - Offers a unique focus on commercialization, examining the current situation and addressing barriers to further commercialization - Includes state-of-the-art, novel approaches for the utilization of biopolymers and their nanoparticles as imprinting matrixes and numerical calculations in the design of MIPs

Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.