Molecular pathology has significantly matured over the past decade to establish itself as a discipline in its own right. Patient diagnosis, prognosis, management and care have been influenced by molecular pathology testing algorithms on a global scale. Whether it pertains to carrier status of deleterious genes, diagnosis by molecular techniques, assessment of appropriate remission post treatment, parentage or forensics testing – molecular pathology continues to increase its presence and influence in the diagnostic laboratory armamentarium. Furthermore, intellectualization and proprietization of molecular pathology with respect to the discovery of new genes and or new techniques continues to pose new challenges of test ownership, legalities, liabilities, widespread acceptance and utility. This issue of Laboratory Clinics seeks to provide selective state of the art understanding of molecular pathology with respect to its relationship to key pathology disciplines as well as the current challenges and promise for the future.

In this issue of Clinics in Laboratory Medicine, guest editor Lauren L. Ritterhouse brings her considerable expertise to the topic of molecular pathology. Experts in the field cover topics such as molecular pathology of lung cancer, gliomas, prostate cancer, and more. - Contains 14 relevant topics including clinical utilization and designing a test menu; molecular alteration in pediatric solid tumors; pan-cancer molecular biomarkers; and more. - Provides in-depth clinical reviews on molecular pathology, offering actionable insights for practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This updated issue of Clinics in Laboratory Medicine, edited by Martin H. Bluth, will focus on Molecular Pathology. Topics include, but are not limited to, The Impact of Molecular Pathology on the Practice of Pathology; Molecular pathology techniques; Clinical Implication of MicroRNAs in Molecular Pathology; Diagnostic Molecular Microbiology; Molecular Pathology in Transfusion Medicine; Molecular Diagnosis of Hematopoietic Neoplasms; Molecular Diagnostics in Colorectal Carcinoma; Molecular Diagnostics in the Neoplasms of Small Intestine and Appendix; Molecular Diagnostics in Esophageal and Gastric Neoplasms; Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gall Bladder, and Extrahepatic Biliary Tract; Current Applications of Molecular Genetic Technologies to the Diagnosis and Treatment of Cutaneous Melanocytic Neoplasms; Breast Carcinoma; and Gynecologic Cancers.

This issue of Clinics in Laboratory Medicine titled, "Conceptual Advances in Pathology" addresses the key factors impacting pathology and details the technology surrounding the field. The Guest Editor, Zoltan Oltvai, MD., splits the issue into three sections; Technological Advances, Process Advances, Educational and Practice Needs, and the Business of Pathology.

This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.

This issue of the Clinics in Laboratory Medicine, edited by Dr. Anil Parwani, is a special issue is devoted to topics in Pathology Informatics. Topics include but are not limited to: Basics of Information Systems (Hardware, Software); Networks, Interfaces and Communications; Databases; Data Representation, Coding and Communication Standards; Laboratory Information Systems; Enhancing and Customizing Laboratory Information Systems; Laboratory Management and Operations; Specialized Laboratory Information Systems; Middleware and Laboratory Automation; Bar Coding and Tracking; Molecular Pathology Informatics; Pathology Informatics and Project Management; Digital Imaging; Telepathology; Healthcare Information Systems; Data Security and Reliability; Role of Informatics in Patient Safety and Quality Assurance; Role of Pathology Informatics in IT Leadership; Selection and Implementation of New Information Systems; Biomedical Informatics and Research Informatics; Training in Pathology Informatics; and more.

This issue of Clinics in Laboratory Medicine, edited by Dr. Dan Milner, will focus on Global Health and Pathology. Topics include, but are not limited to: Clinical Laboratory Volunteerism, Pathologists Overseas; Anatomic Pathology Volunteerism; Funding Strategies in Research and Global Pathology; Diagnostics for Cancer and Health Systems building through pathology laboratories; Training the next pathologists in global health; Maximizing internet resources for improving pathology/lab medicine in LMICs; Pathology-based research in Africa; HIV and Cancer: Role of Pathology in success; Lymphoma and Pathology in Africa: Current approaches and future diagnostics; Laboratory Capacity as a tool for building health systems; Building Cross Country Networks for Laboratory Capacity and improvement; Lab accreditation; Practical success in Telepathology experiences in Africa; Pathology and WHO vision of the future of LMICs; Breast Cancer in LMICs: Why we need pathology and clinical trial capability to solve this challenge; Cytopathology in LMICs: why and how to integrate to capacitate healthcare; and Biorepositories and Data Cores for Research in Global Health.