In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites usually have an anaerobic metabolism, while blood parasites have an aerobic metabolism, intracellular parasites escape the immune system, while extracellular parasites evade the immune system, usually by antigenic variation. Comprehensive genome data now being available allow us to address profound scientific questions, such as which traits enable the parasite to survive in the human host, which to cause disease and which can be used as drug targets. This book intends to give an overview of the state of knowledge on “the molecules” of protozoan parasites – on their genomes, proteomes, glycomes and lipidomes.

A valuable, new source, Molecular Medical Parasitology is the only text of its kind -- one that applies broad concepts and current scientific advances from both molecular biology and biochemistry to the study of parasitic organisms. An internationally renowned team of scientists and physicians places parasites in their broad biological contexts while still emphasizing the specifics that differentiate these organisms. Not only will researchers and faculty in parasitology find this an indispensable guide, physicians will benefit from the thorough coverage molecular biology and biochemistry's current influences on treatment and management of parasitic diseases. - Features the most up-to-date scientific methods behind the medical management of parasitic diseases - Applies the most current synthesis of molecular biology and biochemistry to parasitic organisms - Contains many informative figures and clear illustrations

Enzymes; 8.

Veterinary Clinical Parasitology, Eighth Edition, prepared under the auspices of the American Association of Veterinary Parasitologists (AAVP), emphasizes the morphologic identification of both internal and external parasites of domestic animals. Focusing on the tests and information most relevant to daily practice, the book describes accurate, cost-effective techniques for diagnosing parasitic infections in animals. Including clear, easy-to-find information on the distribution, life cycle, and importance of each parasite, Veterinary Clinical Parasitology offers more than 450 images to aid with diagnosis. The Eighth Edition includes a new chapter on immunologic and molecular diagnosis, increased coverage of ticks and new sections on identification of microfilariae and larvae in diagnostic samples. The new edition also features expanded information on quantitative egg counts, detection of anthelmintic resistance and identification of ruminant strongylid larvae. Additional improvements include many new images throughout the book, revised taxonomic information, a new layout featuring tabs by section to improve user-friendliness, and a companion website offering the images from the book in PowerPoint at www.wiley.com/go/zajac. Veterinary Clinical Parasitology is a highly practical benchside reference invaluable to clinicians, technicians, and students.

Experts present methods and protocols essential for understanding parasites at the molecular level. The protocols cover culturing techniques for the major experimental organisms, methods for isolating and processing nucleic acids and proteins, PCR-based protocols for parasite identification, gene isolation and mutation, antibody-based procedures, chromosome and epitope mapping, flow cytometry, RNA sequencing, and parasite transformation.

Biochemistry of Parasites, Second Edition presents the biochemical aspects of parasitology. The topics covered in the book include inorganic substances; carbohydrate relationships of parasites; parasitic metabolism of carbohydrates and transport mechanisms; distribution of lipids in the bodies of parasites; and disturbances in the host's protein metabolism during parasitic infections. Parasitologists and biochemists will find the book interesting.

Human Parasitology emphasizes the medical aspects of the topic, while incorporating functional morphology, physiology, biochemistry, and immunology to enhance appreciation of the diverse implications of parasitism. Bridging the gap between classical clinical parasitology texts and traditional encyclopaedic treatises, Human Parasitology appeals to students interested not only in the medical aspects of Parasitology but also to those who require a solid foundation in the biology of parasites. - Updated and expanded reference section - New chapter on Immunology - Additional SEM and TEM micrographs - Professionally drawn life cycle illustrations - Addition of "Host Immune Response section for each organism