The study of paleopathology has two very different constituencies, the medical scientist and the zoologist/paleontologist/anthropologist. Their investigative procedures and professional jargon are different, sometimes to the point of mutual incomprehensibility. Paleontologists/anthropologists/zoologists have a limited data base for the characterization and interpretation of pathology. This must come from the human and veterinary medical experience. What, beyond intellectual satisfaction, can the health care community expect from this relationship? The past history of the appearance and dispersal of infectious disease and cancer is of considerable theoretical importance and leads to new insights on the nature and transmission of diseases that are otherwise ambiguous. The discovery of rheumatoid arthritis in pre-Columbian North America exemplifies insights gained. The current effort delineates osseous impact of disease (as manifest in clinical populations diagnosed in life), representation in the zoologic, paleontologic and anthropologic record, and assessment techniques that can be confidently applied. The chapters form “columns” that provide the foundation for scientific critical thinking. The actual integration of the information is in its application. Our purpose is to provide a data base and atlas of actually documented skeletal impact of diseases (as population phenomenon), an initial data base of reported skeletal pathology, and a methodology for expanding this to new arenas. The first section of the book examines the scientific basis of paleopathology, its transition from speculation-based musings, resolution of misconceptions and the denouement of paleo-epidemiology. The second section provides holistic analysis of the gamut of pathology/diseases with significant skeletal impact, with a validated archeologic/zoological/paleontological record. The third section provides a glossary to resolve the semantic challenges inherent to interdisciplinary efforts. The fourth section provides an atlas of pathology representation in the fossil record. Ultimately, this book intends to present a scientifically-validated approach to recognition of disease in the archeological, zoological and paleontological record, superseding previous speculation-based offerings.

This volume presents a truly integrated methodological and biocultural approach to the expanding discipline of human palaeopathology. The book provides researchers and practitioners with a comprehensive guide to the main methods and techniques that are currently available for studying diseases and related conditions from human skeletal remains. It also describes the ways in which these methods can be applied to the reconstruction of health and disease in the past. The first part of the book deals with the survival of palaeopathological evidence and provides an up-to-date account of some of the latest techniques for studying disease in ancient remains. These include imaging techniques, such as radiography and CT scanning, and biochemical and histological analyses. Part two discusses the diagnosis and interpretation of particular classes of disease. The emphasis here is on what can be learnt by taking a biocultural or holistic approach to the study of disease frequencies at a population level. Combines theoretical, methodological and diagnostic aspects with key biocultural approaches. Includes overviews of the latest applicable techniques from molecular biology, biochemistry, histopathology and medical imaging. Written by an international team of experts. This book is an invaluable resource for biological anthropologists and archaeologists who study health and disease in past populations. It is also of interest to medical researchers dealing with epidemiological, diagnostic and pathophysiological aspects of diseases, who need a perspective upon the ways in which particular diseases affected earlier generations. Praise from the reviews: “... This book offers an impressive amount of information for both students and more advanced researchers. Its value lies in the vast expertise the contributors have to offer, with all of them being experts with long-standing careers in their respective fields, as well as the geographical distribution of examples that are given to illustrate specific diseases... outstanding and it truly is an important resource for anyone interested in palaeopathology.” PALEOPATHOLOGY NEWSLETTER “The strengths of the book are numerous, but I am especially impressed with the clarity of presentation... I strongly recommend the book, and plan on using it in my classes as assigned reading to emphasize the very complex nature of diagnosis and its essential role of providing baseline information for interpreting health profiles of ancient populations.” THE QUARTERLY REVIEW OF BIOLOGY “It may be asked if we really need yet another book on paleopathology, especially because there are many acclaimed sources available. In this case, the answer must be a resounding ‘‘Yes!’’...Visually and textually, this volume is of exceptional value for guiding future generations of paleopathologists.” AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY "Pinhasi and Mays have produced an excellent, balanced compilation that reflects what is currently happening in paleopathology research and that nicely addresses paleopathology as both discipline and tool, highlighting technical advanced and schooling us on how disease manifests in the human skeleton. This is valuable resource that students and professionals interested in human paloepathology should consider adding to their libraries." AMERICAN JOURNAL OF HUMAN BIOLOGY

A Companion to Paleopathology offers a comprehensive overview of this rapidly growing sub- field of physical anthropology. Presents a broad overview of the field of paleopathology, integrating theoretical and methodological approaches to understand biological and disease processes throughout human history Demonstrates how paleopathology sheds light on the past through the analysis of human and non-human skeletal materials, mummified remains and preserved tissue Integrates scientific advances in multiple fields that contribute to the understanding of ancient and historic diseases, such as epidemiology, histology, radiology, parasitology, dentistry, and molecular biology, as well as archaeological, archival and historical research. Highlights cultural processes that have an impact on the evolution of illness, death and dying in human populations, including subsistence strategies, human environmental adaptations, the effects of malnutrition, differential access to resources, and interpersonal and intercultural violence

Paleopathology is designed to help bone specialists with diagnosis of diseases in skeletal assemblages. It suggests an innovative method of arriving at a diagnosis in the skeleton by applying what are referred to as "operational definitions." The aim is to ensure that all those who study bones will use the same criteria for diagnosing disease, which will enable valid comparisons to be made between studies. This book is based on modern clinical knowledge and provides background information so that those who read will understand the natural history of bone diseases, and this will enable them to draw reliable conclusions from their observations. Details of bone metabolism and the fundamentals of basic pathology are also provided, as well as a comprehensive and up-to-date bibliography. A short chapter on epidemiology provides information on how best to analyze and present the results of a study of human remains.

Ortner's Identification of Pathological Conditions in Human Skeletal Remains, Third Edition, provides an integrated and comprehensive treatment of the pathological conditions that affect the human skeleton. As ancient skeletal remains can reveal a treasure trove of information to the modern orthopedist, pathologist, forensic anthropologist, and radiologist, this book presents a timely resource. Beautifully illustrated with over 1,100 photographs and drawings, it provides an essential text and material on bone pathology, thus helping improve the diagnostic ability of those interested in human dry bone pathology. Presents a comprehensive review of the skeletal diseases encountered in archaeological human remains Includes more than 1100 photographs and line drawings illustrating skeletal diseases, including both microscopic and gross features Based on extensive research on skeletal paleopathology in many countries Reviews important theoretical issues on how to interpret evidence of skeletal disease in archaeological human populations

Giving students opportunities to read like mathematicians as they explore content has the potential to move their thinking and understandings in monumental ways. Each chapter presented in this volume provides readers with approaches and activities for pairing a young adult novel with specific mathematics concepts. Chapters include several instructional activities for before, during, and after reading as well as extension activities that move beyond the text as students continue to develop mathematical literacy.

This is the Second Edition of a well-received book that reflects a fresh, integrated coverage of the concepts and scientific measurement of stress and welfare of animals including humans. This book explains the basic biological principles of coping with many forms of adversity. The major part of this work is devoted to explaining scientifically usable concepts in stress and welfare. A wide range of welfare indicators are highlighted in detail with examples being drawn from man and other species. The necessity for combining information from disciplines is emphasized with a one-health, one-welfare approach. This information forms the basis for a synthesis of new ideas. Among the issues covered are: - How brain and body systems regulate using feelings, physiological responses, behaviour and responses to pathology - Limits to adaptation - Assessing positive and negative welfare during both short-term and long-term situations - Ethical problems and suggested solutions A proper assessment of animal welfare is essential to take informed decisions about what is morally acceptable in terms of practice and in the development of a more effective legislation. This work encapsulates a very wide body of literature on scientific aspects of animal welfare and will thus prove a valuable asset for animal welfare scientists, psychologists, students and teachers of all forms of biology, behaviour, medicine, veterinary medicine and animal usage.