Originally published in 1979, this book discusses how the physical and chemical properties of disordered systems such as liquids, glasses, alloys, amorphous semiconductors, polymer solutions and magnetic materials can be explained by theories based on a variety of mathematical models, including random assemblies of hard spheres, tetrahedrally-bonded networks and lattices of 'spins'. The text describes these models and the various mathematical theories by which the observable properties are derived. Techniques and concepts such as the mean field and coherent approximations, graphical summation, percolation, scaling and the renormalisation group are explained and applied. This book will be of value to anyone with an interest in theoretical and experimental physics.

Understanding the effect of disorder on critical phenomena is a central issue in statistical mechanics. In probabilistic terms: what happens if we perturb a system exhibiting a phase transition by introducing a random environment? The physics community has approached this very broad question by aiming at general criteria that tell whether or not the addition of disorder changes the critical properties of a model: some of the predictions are truly striking and mathematically challenging. We approach this domain of ideas by focusing on a specific class of models, the "pinning models," for which a series of recent mathematical works has essentially put all the main predictions of the physics community on firm footing; in some cases, mathematicians have even gone beyond, settling a number of controversial issues. But the purpose of these notes, beyond treating the pinning models in full detail, is also to convey the gist, or at least the flavor, of the "overall picture," which is, in many respects, unfamiliar territory for mathematicians.

Written by distinguished academic and Editor of the British Journal of Psychiatry, and a now retired NHS consultant psychiatrist, this latest edition of Models for Mental Disorders reflects the significant changes in clinical practice and understanding in the last four years. With increased emphasis on the multidisciplinary approach now being used in all mental health facilities in Europe, the two new chapters on application of models in multidisciplinary teams and how understanding of models improves communication are particularly timely and relevant. The book also features an easy-to-read new appendix providing a glossary of commonly-used terms in psychiatry for the interested lay-reader. An adopted title on many psychology courses throughout the UK, this fourth edition continues to provide an invaluable introduction to the different models used in evaluating mental health, and is recommended reading for all those interested in mental health and illness.

Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research. - Focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders - Serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals - Discusses specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders

Mice are used as model organisms across a wide range of fields in science today—but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior, Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field. Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson’s extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much—if not more—about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm.

With contributions from prominent experts, this pragmatic book takes a close look at the nature of complex psychological trauma in children and adolescents and the clinical challenges it presents. Each chapter shows how a complex trauma perspective can provide an invaluable unifying framework for case conceptualization, assessment, and intervention amidst the chaos and turmoil of these young patients' lives. A range of evidence-based and promising therapies are reviewed and illustrated with vivid case vignettes. The volume is grounded in clinical innovations and cutting-edge research on child and adolescent brain development, attachment, and emotion regulation, and discusses diagnostic criteria, including those from DSM-IV and DSM-5. See also Drs. Ford and Courtois's edited volume Treating Complex Traumatic Stress Disorders in Adults, Second Edition, and their authored volume, Treatment of Complex Trauma: A Sequenced, Relationship-Based Approach.

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.