Single-Cell-Based Models in Biology and Medicine
Title | Single-Cell-Based Models in Biology and Medicine PDF eBook |
Author | Alexander Anderson |
Publisher | Springer Science & Business Media |
Pages | 346 |
Release | 2007-08-08 |
Genre | Mathematics |
ISBN | 376438123X |
Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.
Mathematical Modeling in Systems Biology
Title | Mathematical Modeling in Systems Biology PDF eBook |
Author | Brian P. Ingalls |
Publisher | MIT Press |
Pages | 423 |
Release | 2022-06-07 |
Genre | Science |
ISBN | 0262545829 |
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Modelling in Medicine and Biology VIII
Title | Modelling in Medicine and Biology VIII PDF eBook |
Author | C. A. Brebbia |
Publisher | WIT Press |
Pages | 353 |
Release | 2009 |
Genre | Technology & Engineering |
ISBN | 1845641833 |
Featuring contributions from the eighth International Conference on Modelling in Medicine and Biology, this volume covers a broad spectrum of topics including the application of computers to simulate biomedical phenomena. It will be of interest to medical and physical scientists and engineers.
Modelling in Medicine and Biology
Title | Modelling in Medicine and Biology PDF eBook |
Author | |
Publisher | |
Pages | |
Release | 2005 |
Genre | |
ISBN |
Modelling in Medicine and Biology X
Title | Modelling in Medicine and Biology X PDF eBook |
Author | R. Kiss |
Publisher | WIT Press |
Pages | 301 |
Release | 2013 |
Genre | Technology & Engineering |
ISBN | 1845647068 |
This book contains the proceedings of the tenth in a series of biennial conferences on the topic of advances in medical and biological computation that began in 2001. The advances covered in the computer modelling, and computational methods and measurements, and their integration, have applications in the study of orthopaedics, cardiovascular systems biomechanics and electrical simulation, amongst others, and are leading to progress in medical care and treatment.The conference topics cover a broad spectrum including the simulation of biomedical problems, ranging from cardiovascular modelling to virtual reality and simulation in surgery.
Modelling in Medicine and Biology VI
Title | Modelling in Medicine and Biology VI PDF eBook |
Author | Mauro Ursino |
Publisher | WIT Press |
Pages | 573 |
Release | 2005 |
Genre | Science |
ISBN | 1845640241 |
Featuring contributions from the Sixth International Conference on Modelling in Medicine and Biology, this volume covers a broad spectrum of topics including the application of computers to simulate biomedical phenomena. It will be of interest both to medical and physical scientists and engineers and to professionals working in medical enterprises actively involved in this field.Areas highlighted include: Simulation of Physiological Processes; Computational Fluid Dynamics in Biomedicine; Orthopaedics and Bone Mechanics; Simulations in Surgery; Design and Simulation of Artificial Organs; Computers and Expert Systems in Medicine; Advanced Technology in Dentistry; Gait and Motion Analysis; Cardiovascular System; Virtual Reality in Medicine; Biomechanics; and Neural Systems.
Modeling Methods for Medical Systems Biology
Title | Modeling Methods for Medical Systems Biology PDF eBook |
Author | María Elena Álvarez-Buylla Roces |
Publisher | |
Pages | 258 |
Release | 2018 |
Genre | Bioinformatics |
ISBN | 9783319893556 |
This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.