This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. Peptides are important biological molecules and have various physiological actions. Peptide-based drug discovery may help bring about the development of useful medicines that are highly safe and show potent pharmacological effects in small doses. Recently, it has been shown that there is an important drug-like space in the mid-sized region between low- and high-molecular-weight compounds. Thus, mid-size drugs such as peptide compounds are being focused on. To date, several peptidomimetics that mimic primary, secondary, and tertiary structures of peptides have been developed to maintain and improve biological activities and actions of peptides. In this book, the features and advantages of mid-size drugs are described in detail. In addition, the merits of utilizing peptidomimetics in the development of mid-size drugs are referred to. Understanding such peptide-derived mid-size drugs will lead to a comprehensive expansion of medicinal chemistry.

If you have ever attempted to research the AIDS epidemic or the HIV virus, you have discovered the overwhelming array of information sources. How do you know which information is the most accurate and most current? This second edition contains a directory of sources and resources in the AIDS information arena, designed to make it easy for anyone to find information on AIDS.Important Topics Covered: Organizations--includes AIDS service organizations, community-based organizations, and organizations operating at the local, regional, state, and national level Health Departments--identifies state offices, including the District of Columbia, that provide AIDS-related information or that can refer individuals to the appropriate organization Research Institutions, Grant Funding Sources, Education and Training Centers, and Federal Agencies Hotlines--both local and national Electronic Sources of Information--includes specific journals, bibliographies, and monographs Audiovisual Producers--covers producers of audiovisuals concerning AIDSThe organization of the directory and the indexes, arranged geographically as well as alphabetically, are compelling features of this timely book. How to Find Information About AIDS, Second Edition is a valuable addition to the reference collection of librarians, counselors, school teachers, AIDS organization administrators, and medical personnel.

This book focuses on searching and hands-on experience, which makes the text suitable for those who wish to learn searching for their own use as well. It is intended for those who will act as search intermediaries, accepting questions from clients and performing the searches.