The first reports on the application of microwaves in organicsynthesis date back to 1986, but it was not until the recentintroduction of specifically designed and constructed equipment,which countered the safety and reproducibility concerns, thatsynthetic application of microwaves has become established as alaboratory technique. Microwave assisted synthesis is now beingadopted in many industrial and academic laboratories to takeadvantage of the novel chemistry that can be carried out using avariety of organic reaction types. This book demonstrates the underlying principles of microwavedielectric heating and, by reference to a range of organic reactiontypes, it's effective use in synthetic organic chemistry. Toillustrate the impact microwave assisted organic synthesis can haveon chemical research, case studies drawn mainly from thepharmaceutical industry are presented.

With the novice user in mind, this beginner's guide explains thebasics behind microwave technology, evaluates available instrumentsand reaction modes, and provides practical hints for everyeventuality. Includes 27 detailed protocols for often-usedreactions. From the contents: 1 Microwave Synthesis - An Introduction 2 Microwave Theory 3 Equipment Review 4 Microwave Processing Techniques 5 Starting With Microwave Chemistry 6 Experimental Protocols 6.1 General Small-Scale Sealed-Vessel Microwave Processing 6.2 Reaction Optimization 6.3 Library Generation 6.4 Reaction Scale-Up 6.5 Special Processing Techniques

Microwave Chemistry has changed the way to work in chemical laboratories and is an established state-of-the-art technology to accelarate and enhance chemical processes. This book not only gives an overview of the technology, its historical development and theoretical background, but also presents its exceptionally broad spectrum of applications. Microwave Chemistry enables graduate students and scientist to learn and apply its methods successfully.

1. Introduction to microwave chemistry 11; 2. Solvents 29; 3. Chemical reactions in the presence and absence of solvent 77; 4. Synthetic applications 95; 5. Getting started with microwave synthesis 157; 6. Microwave safety considerations 175; 7. Microwave hardware 181.

The demands for green and sustainable synthetic methods in the fields of healthcare and fine chemicals, combined with the pressure to produce these substances expeditiously and in an environmentally benign fashion, pose significant challenges to the synthetic chemical community. Green chemistry can avoid pollution by utilizing techniques that are environmentally friendly by design and one of the best green techniques is the use of microwave (MW) assisted aqueous synthetic protocols. Fusing MW technique with water (as a benign reaction medium) can offer an extraordinary synergistic effect with greater potential than these two individual components in isolation. Selective microwave heating can be exploited to develop a high yield protocol and the use of water expedites the MW-protocol with more energy efficiency. This book provides an overview of the various processes developed using aqueous microwave chemistry and is written for chemists, chemical engineers and researchers in the early stages who want to develop sustainable and green processes. Written by well known microwave experts, the book is a comprehensive examination of the field and is the first book that deals strictly with aqueous microwave chemistry and represents a significant effort towards green chemistry. It covers all the microwave-assisted aqueous reactions in depth, including heterocycle synthesis, metal catalysis, enzyme catalysis, polymer synthesis, nanomaterials synthesis and nano-catalysis. Each chapter contains representative experimental procedures, helping the reader quickly replicate some of the experiments to gain hands-on experience.

For the first time, this comprehensive handbook presents the emerging field of microwave technology for the synthesis of nanoparticles. Divided into three parts--fundamentals, methods, and applications--it covers topics including microwave theory, scale-up, microwave plasma synthesis, characterization, and more. This offers both an important volume for academic researchers, and a resource for those in industry exploring the applications of nanoparticles in semiconductors, electronics, catalysis, sensors, and more.

A comprehensive overview covering the principles and preparation of catalysts, as well as reactor technology and applications in the field of organic synthesis, energy production, and environmental catalysis. Edited and authored by renowned and experienced scientists, this reference focuses on successful reaction procedures for applications in industry. Topics include catalyst preparation, the treatment of waste water and air, biomass and waste valorisation, hydrogen production, oil refining as well as organic synthesis in the presence of heterogeneous and homogeneous catalysts and continuous-flow reactions. With its practical relevance and successful methodologies, this is a valuable guide for chemists at universities working in the field of catalysis, organic synthesis, pharmaceutical or green chemistry, as well as researchers and engineers in the chemical industry.