Microarray Methods for Drug Discovery
Title | Microarray Methods for Drug Discovery PDF eBook |
Author | Sridar V. Chittur |
Publisher | Humana |
Pages | 285 |
Release | 2016-08-23 |
Genre | Medical |
ISBN | 9781493957392 |
Authoritative and cutting-edge, this book provides a single volume reference for all types of microarrays. It supplies new information on microarrays for cytogenetics and drug metabolism, and covers a wide range of microarray platforms.
Microarray Innovations
Title | Microarray Innovations PDF eBook |
Author | Gary Hardiman |
Publisher | CRC Press |
Pages | 362 |
Release | 2009-04-02 |
Genre | Medical |
ISBN | 1420094513 |
In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarr
Applying Genomic and Proteomic Microarray Technology in Drug Discovery
Title | Applying Genomic and Proteomic Microarray Technology in Drug Discovery PDF eBook |
Author | Robert S. Matson |
Publisher | CRC Press |
Pages | 260 |
Release | 2004-12-28 |
Genre | Medical |
ISBN | 0203491130 |
Microarrays play an increasingly significant role in drug discovery. Written by a leader in the field, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. The author addresses the drawbacks, helping
Methods and Techniques in Drug Discovery
Title | Methods and Techniques in Drug Discovery PDF eBook |
Author | John Sterling |
Publisher | |
Pages | 284 |
Release | 2005 |
Genre | Computers |
ISBN |
Microarray Methods and Protocols
Title | Microarray Methods and Protocols PDF eBook |
Author | Robert S. Matson |
Publisher | CRC Press |
Pages | 216 |
Release | 2009-01-20 |
Genre | Medical |
ISBN | 1420046667 |
A Step-by-Step Guide to Present and Future Uses of Microarray TechnologyMicroarray technology continues to evolve, taking on a variety of forms. From the spotting of cDNA and the in situ synthesis of oligonucleotide arrays now come microarrays comprising proteins, carbohydrates, drugs, tissues, and cells. With contributions from microarray experts
Methods in Microarray Normalization
Title | Methods in Microarray Normalization PDF eBook |
Author | Phillip Stafford |
Publisher | CRC Press |
Pages | 322 |
Release | 2008-01-31 |
Genre | Mathematics |
ISBN | 1420052799 |
This organized text compiles, for the first time, the most useful normalization methods developed for interpreting microarray data. Experts examine the mathematical processes that are important in normalizing data and avoiding inherent systematic biases. They also review modern software, including discussions on key algorithms, comparative data, and download locations. The book contains the latest microarray innovations from companies such as Agilent, Affymetrix, and GeneGo as well as new, readily adaptable normalization methods for expression and CGH arrays. It also lists of open-source molecular profiling normalization algorithms available and where to access them.
Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition
Title | Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition PDF eBook |
Author | Robert S. Matson |
Publisher | CRC Press |
Pages | 325 |
Release | 2013-03-13 |
Genre | Medical |
ISBN | 1439855633 |
Microarrays play an increasingly significant role in drug discovery. The commercial landscape has changed dramatically over the past few years and researchers have made great advancements with regard to construction and use. Now in its second edition, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. Updated and revised to reflect recent progress in the field, the second edition discusses: Expanded omics-driven applications, including the areas of metabolomics and chemical biology The commercialization of the microarray platform, with a historical perspective aimed at recognizing key technological developments Solid-supports (substrates) and surface chemistries currently used in the creation of nucleic acid and protein microarrays Different approaches to producing microarrays that achieve spot equality with the same number of molecules properly oriented The development of the gene expression microarray and representative applications The development of protein microarray technology, including its history and key applications Unique to this edition is a new chapter on multiplex assays that examines the development and applications of arrays across diverse platforms. It discusses applications for qPCR, multiplex lateral flow, and multiplex bead assays. It also presents platform-to-platform comparisons. Microarrays remain an invaluable tool for omics-based research not only in drug discovery, but in the life sciences, in clinical research, and for diagnostic applications worldwide. This volume presents the current state of the art on the utility of this technology to solve a host of important biological problems.