Methods for Synaptic Interrogation
Title | Methods for Synaptic Interrogation PDF eBook |
Author | Dirk Feldmeyer |
Publisher | Frontiers Media SA |
Pages | 276 |
Release | 2020-07-14 |
Genre | |
ISBN | 2889638642 |
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Recent Advances in Measuring and Controlling Synaptic Communication
Title | Recent Advances in Measuring and Controlling Synaptic Communication PDF eBook |
Author | Jacopo Lamanna |
Publisher | Frontiers Media SA |
Pages | 117 |
Release | 2023-11-10 |
Genre | Science |
ISBN | 2832536379 |
Synapses represent a unique neuronal compartment specialized in communication. The morpho-functional investigation of the synapse has always been hindered by its tiny size and high density of molecular elements, but specific technological and methodological advances helped us to reduce these limitations. As the matter of fact, in recent years, we have witnessed the continuous development of new methods allowing measuring and controlling synaptic activation both in vitro and in vivo. These include new genetically encoded sensors of synaptic exo-endocytosis, but also engineered synaptic proteins able to inhibit the release of neurotransmitters. Furthermore, new promising tools allow changing the functional properties of synapses in a plasticity-like manner. All these methodological advances are likely to generate unprecedented knowledge about the dynamics of synaptic transmission and plasticity at several levels of the nervous system. Nevertheless, in most cases, the implementation of these new methods remains technically demanding, likely due to the high complexity of their operating principle. Hence, it would be worth refining and potentiating these tools in order to extend the range of experimental settings for their application.
Neurotransmitter Release
Title | Neurotransmitter Release PDF eBook |
Author | Hugo J. Bellen |
Publisher | Oxford University Press, USA |
Pages | 466 |
Release | 1999 |
Genre | Medical |
ISBN |
This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.
Biology of Brain Disorders – Cellular substrates for disrupted synaptic function and experience-dependent plasticity
Title | Biology of Brain Disorders – Cellular substrates for disrupted synaptic function and experience-dependent plasticity PDF eBook |
Author | Daniela Tropea |
Publisher | Frontiers Media SA |
Pages | 202 |
Release | 2022-09-26 |
Genre | Science |
ISBN | 2832500722 |
New Techniques in Systems Neuroscience
Title | New Techniques in Systems Neuroscience PDF eBook |
Author | Adam D. Douglass |
Publisher | Springer |
Pages | 309 |
Release | 2015-04-13 |
Genre | Science |
ISBN | 3319129139 |
This volume is essential reading for anyone wishing to understand the recent explosion of experimental tools in neuroscience that now make it possible to manipulate, record, and understand neuronal activity within the intact brain, and which are helping us learn how the many neurons that comprise a network act together to control behavior. Leaders in the field discuss the latest developments in optogenetics, functional imaging, circuit mapping, and the application of these tools to complex biological problems.
All-Optical Methods to Study Neuronal Function
Title | All-Optical Methods to Study Neuronal Function PDF eBook |
Author | Eirini Papagiakoumou |
Publisher | Springer Nature |
Pages | 424 |
Release | 2023-02-20 |
Genre | Medical |
ISBN | 1071627643 |
This open access volume provides an overview of the latest methods used to study neuronal function with all-optical experimental approaches, where light is used for both stimulation and monitoring of neuronal activity. The chapters in this book cover topics over a broad range, from fundamental background information in both physiology and optics in the context of all-optical neurophysiology experiments, to the design principles and hardware implementation of optical methods used for photoactivation and imaging. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, All-Optical Methods to Study Neuronal Function is a valuable resource for researchers in various disciplines such as physics, engineering, and neuroscience. This book will serve as a guide to establish useful references for groups starting out in this field, and provide insight on the optical systems, actuators, and sensors. This is an open access book.
The Claustrum
Title | The Claustrum PDF eBook |
Author | John R. Smythies |
Publisher | Academic Press |
Pages | 408 |
Release | 2013-11-11 |
Genre | Medical |
ISBN | 012404722X |
The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum's two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain's orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon. - Develops a unifying hypothesis about the claustrum's role in consciousness, as well as the integration of sensory information and other higher brain functions - Discusses the involvement of the claustrum with autism, schizophrenia, epilepsy, Alzheimer's disease, and Parkinson's disease - Coverage of all aspects of the claustrum, from its evolution and development to promising new lines of research, including epigenetics, provides a platform and point of reference for future investigative efforts