Since the major pioneering of joint replacement surgery more than fifty years ago, much research and progress has been made in the field of arthroplasty with new insights into better materials, types of cement and bone-cell compatible coatings, and a better understanding of the causes of implant failure. With an increasingly ageing population the requirement for arthroplastic surgery is manifest; over 800,000 hips worldwide are replaced each year, and replacement surgery is performed for almost every joint of the body. The Engineering of Human Joint Replacements covers the design, engineering, production and manufacture of human joint replacements, as well as associated engineering concerns such as surface coatings, orthopedic bone cement, the causes and effects of wear and tear, and rapid prototyping for clinical evaluation. Materials evaluation and selection is discussed, as well as production processes and insertion methods. The author provides an overview of skeletal anatomy and the effects of pain and deterioration in order to put the engineering principles into a medical context. Examples of joint replacements for the most common regions of the body are included, and aspects of clinical studies of these cases are discussed. Key Features: • Provides an overview of the engineering materials and processes involved in the manufacture of human joint replacements • Sets the scene for engineers and clinicians embarking on research into joint replacements • Includes clinical and industrial examples and points the way to future developments • Provides information on medical device companies with an engineering guide to the requirements for joint replacement The Engineering of Human Joint Replacements bridges the divide between engineering and orthopaedic surgery, offering an introductory text to young engineers entering the field, as well as a reference for medical staff who will benefit from an understanding of the materials and methods used in their design, engineering and manufacture.

Cannulated Screw Fixation is the first volume of its kind to provide both the biomechanics of these screw systems as well as complete operative techniques. This book teaches the orthopaedic surgeon and resident all aspects of cannulated screw fixation from principles (biomechanics, design, materials, manufacturing) to clinical uses including anatomy, imaging techniques, advantages, complications and outcomes. This comprehensive text includes chapters written by well-known orthopaedists in their respective anatomical areas with material on preferred operating techniques and uses in more specialized clinical situations for both upper and lower extremities. Edited by pioneers in the development of the cannulated screw this volume is a "must have" for all orthopaedic surgeons and residents.

This book addresses the background and significance of the factors potentially influencing the clinical and biological outcomes of metal-on-metal hip implants. Metal-on-metal bearings were introduced and evaluated as an alternative to other bearing couples, particularly metal-on-polyethylene, due to their enhanced wear resistance as determined in laboratory testing. Initially, reports of short-term clinical outcomes were favorable and an increasing number of metal-on-metal prostheses were implanted. Subsequently, isolated case findings describing adverse tissue responses around the articulation became the harbinger of an increasing number of reports describing pseudotumors and other significant lymphocytic-based responses associated with metal-on-metal prostheses. Questions have been raised as to whether this is an implant, design, or patient-specific response. The reasons why some patients have a negative biological response and pathology while others do not remain to be determined, but tens of thousands of patients in the US, the UK, and around the world are considered to be at risk. Leading researchers and clinicians describe the issues related to the nature of the biological and pathological responses and the protocols that should be followed to determine if an adverse response is occurring. This book is essential reading for researchers, engineers, and orthopaedic surgeons who are involved in the design, evaluation, and implantation of metal-on-metal prostheses.

Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites