The first consolidated textbook explaining the mechanism of clinical signs commonly seen in medicine. Mechanisms of Clinical Signs is the first consolidated text of its kind; designed to help medical students and junior doctors understand the pathophysiological mechanisms behind clinical signs. Unlike existing clinical examination textbooks which are predominantly organised by disease systems and states, Mechanisms of Clinical Signs is arranged by body system; bridging the gap between identifying clinical signs and understanding the causes behind them. Presented in a useful handbook style, Mechanisms of Clinical Signs discusses the evidence base and clinical value of each clinical sign to assist with interpretation. Examples are plentiful and include such signs as distinctive tremors in a Parkinson's disease patient and red hands on a patient with liver disease. As well as being an easy-to-follow reference for clinical signs seen on the ward, Mechanisms of Clinical Signs is an excellent study aid - particularly useful for those preparing for 'Viva' or 'OSCE' practical stations. The ability to accurately identify and interpret clinical signs of disease upon examination is a vital first step in correct diagnosis and treatment. Mechanisms of Clinical Signs is therefore an essential textbook for medical students and new practitioners. Online StudentConsult resources accompany Mechanisms of Clinical Signs upon purchase.

Pathophysiology – what is the cause? Clinical significance – what does it mean? Diagnosis and treatment – what is the predictive value? These are questions that all clinicians should continue to ask themselves from the very beginning of medical training and throughout a lifetime of practice. Organised by body system, Mechanisms of Clinical Signs 3e describes the underlying pathway, differential diagnoses and value of the clinical signs seen during physical examination. - Alphabetical listing of clinical signs - Index by sign and conditions for easy reference - Additional flow diagrams - Clinical Pearls highlighting important clinical signs - Summary of the evidence - Access to chapter-based MCQs Access StudentConsult for: - Clinical videos and audio of key signs - Case-based MCQs - An Enhanced eBook. The enhanced eBook allows the end user to access all of the text, figures, and references from the book on a variety of devices.

A textbook on clinical skills. It provides a source of learning and reference for undergraduate medical students and postgraduate doctors. It seeks to teach an integrated approach to clinical practice, so that new methods and investigations are grafted onto established patterns of clinical practice, rather than added on as something extra.

Many published books that comment on the medical model have been written by doctors, who assume that readers have the same knowledge of medicine, or by those who have attempted to discredit and attack the medical practice. Both types of book have tended to present diagnostic categories in medicine as universally scientifically valid examples of clear-cut diseases easily distinguished from each other and from health; with a fixed prognosis; and with a well-understood aetiology leading to disease-reversing treatments. These are contrasted with psychiatric diagnoses and treatments, which are described as unclear and inadequate in comparison. The Medical Model in Mental Health: An Explanation and Evaluation explores the overlap between the usefulness of diagnostic constructs (which enable prognosis and treatment decisions) and the therapeutic effectiveness of psychiatry compared with general medicine. The book explains the medical model and how it applies in mental health, assuming little knowledge or experience of medicine, and defends psychiatry as a medical practice.

Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.

This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice

As with the two previous editions, Barile’s Clinical Toxicology: Principles and Mechanisms, Third edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. With special emphasis placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs, the new edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. The new edition presents the latest, up-to-date protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology. In addition, the effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered. KEY FEATURES • Discusses source of the drug or chemical, pharmacological and toxicological mechanisms of action, detection, identification, and treatment • Examines the complex interactions associated with clinical toxicological events • Emphasizes the signs and symptoms of diseases and pathology caused by toxins and clinical drugs • Covers effect of toxins on body systems and drug-induced adverse reactions • Offers a unique perspective for toxicology, pharmacology, pharmacy and health professions students The target audience for this book is undergraduate and graduate toxicology students, clinical pharmacy (Pharm.D.) students, emergency medical personnel, regulatory agencies, and other related health science professionals. It satisfies an essential need for a concise yet detailed authoritative, fundamental text addressing the current principles of clinical toxicology.