Cancer research has reached a major turning point. The quality and quantity of information gathered about this disease in the past twenty years has revolutionized our understanding of its origins and behavior. No one is better qualified to comment on these dramatic leaps forward than molecular biologist Robert A. Weinberg, director of one of the leading cancer research centers in the world. In One Renegade Cell , Weinberg presents an accessible and state-of-the-art account of how the disease begins and how, one day, it will be cured. Weinberg tells how the roots of cancer were uncovered in 1909 and when the first cancer-causing virus was discovered. He then moves forward to the discovery of the role of chemical carcinogens and radiation in triggering cancer, and relates the remarkable story of the discoveries of oncogenes and tumor suppressor genes, the master controllers of normal and malignant cell proliferation. This book, which presumes little prior knowledge of biology, describes the revolution in biomedical research that has finally uncovered the forces driving malignant growth. Drawing on insights that simply were not available until recently, the discoveries presented in One Renegade Cell have already begun to profoundly alter the way that we diagnose and treat human cancers.

Yohji Yamamoto is a man who understands the power of endurance. The product of a Japanese culture ravaged by war, the progressive designer has built his 50-some year career on perseverance and a refusal to bend to the will of tradition. From his initial struggles as an emerging designer to his incendiary debut on the world stage, all the way through to the near collapse of his company in the wake of the global financial crisis, Yamamoto has overcome every obstacle in his path - and always on his own terms. Today, his eponymous brand offering both men's and women's clothing remains his most commercially successful venture alongside the popular sub-label Y's and youth line Ground Y to its' principal lines Pour Homme and Costume D'Homme. In 2018 the brand evolved yet again expanding into a line of perfume. His innovation has led to groundbreaking collaborations and pop culture moments, working alongside household names of fashion, reinventing icons Like Dr Martins whilst dressing icons of entertainment from Tina Turner to Elton John. Most particularly his trailblazing Y-3 range with street-sports giant Adidas, spurned a new wave of cross-genre collaborations paving the way for the now billion dollar athleisure industry. Raised by his mother, who worked as a dressmaker. Yamamoto found himself identifying more with the women of his life. His compassion for the opposite gender would eventually present itself through the construction of his couture. His collections are built primarily around the comfort and confidence clothing can provide for women, uninterested in presenting them as objects of male desire.

2020 Anisfield-Wolf Book Award Winner Finalist for the National Book Critics Circle Award From an award-winning historian comes a dazzling history of the birth of cultural anthropology and the adventurous scientists who pioneered it—a sweeping chronicle of discovery and the fascinating origin story of our multicultural world. A century ago, everyone knew that people were fated by their race, sex, and nationality to be more or less intelligent, nurturing, or warlike. But Columbia University professor Franz Boas looked at the data and decided everyone was wrong. Racial categories, he insisted, were biological fictions. Cultures did not come in neat packages labeled "primitive" or "advanced." What counted as a family, a good meal, or even common sense was a product of history and circumstance, not of nature. In Gods of the Upper Air, a masterful narrative history of radical ideas and passionate lives, Charles King shows how these intuitions led to a fundamental reimagining of human diversity. Boas's students were some of the century's most colorful figures and unsung visionaries: Margaret Mead, the outspoken field researcher whose Coming of Age in Samoa is among the most widely read works of social science of all time; Ruth Benedict, the great love of Mead's life, whose research shaped post-Second World War Japan; Ella Deloria, the Dakota Sioux activist who preserved the traditions of Native Americans on the Great Plains; and Zora Neale Hurston, whose studies under Boas fed directly into her now classic novel, Their Eyes Were Watching God. Together, they mapped civilizations from the American South to the South Pacific and from Caribbean islands to Manhattan's city streets, and unearthed an essential fact buried by centuries of prejudice: that humanity is an undivided whole. Their revolutionary findings would go on to inspire the fluid conceptions of identity we know today. Rich in drama, conflict, friendship, and love, Gods of the Upper Air is a brilliant and groundbreaking history of American progress and the opening of the modern mind.

This book develops the idea that since decolonisation, regional patterns of security have become more prominent in international politics. The authors combine an operational theory of regional security with an empirical application across the whole of the international system. Individual chapters cover Africa, the Balkans, CIS Europe, East Asia, EU Europe, the Middle East, North America, South America, and South Asia. The main focus is on the post-Cold War period, but the history of each regional security complex is traced back to its beginnings. By relating the regional dynamics of security to current debates about the global power structure, the authors unfold a distinctive interpretation of post-Cold War international security, avoiding both the extreme oversimplifications of the unipolar view, and the extreme deterritorialisations of many globalist visions of a new world disorder. Their framework brings out the radical diversity of security dynamics in different parts of the world.

Black & white print. Principles of Management is designed to meet the scope and sequence requirements of the introductory course on management. This is a traditional approach to management using the leading, planning, organizing, and controlling approach. Management is a broad business discipline, and the Principles of Management course covers many management areas such as human resource management and strategic management, as well as behavioral areas such as motivation. No one individual can be an expert in all areas of management, so an additional benefit of this text is that specialists in a variety of areas have authored individual chapters.

Teaching at Its Best This third edition of the best-selling handbook offers faculty at all levels an essential toolbox of hundreds of practical teaching techniques, formats, classroom activities, and exercises, all of which can be implemented immediately. This thoroughly revised edition includes the newest portrait of the Millennial student; current research from cognitive psychology; a focus on outcomes maps; the latest legal options on copyright issues; and how to best use new technology including wikis, blogs, podcasts, vodcasts, and clickers. Entirely new chapters include subjects such as matching teaching methods with learning outcomes, inquiry-guided learning, and using visuals to teach, and new sections address Felder and Silverman's Index of Learning Styles, SCALE-UP classrooms, multiple true-false test items, and much more. Praise for the Third Edition of Teaching at Its BestEveryone veterans as well as novices will profit from reading Teaching at Its Best, for it provides both theory and practical suggestions for handling all of the problems one encounters in teaching classes varying in size, ability, and motivation." Wilbert McKeachie, Department of Psychology, University of Michigan, and coauthor, McKeachie's Teaching TipsThis new edition of Dr. Nilson's book, with its completely updated material and several new topics, is an even more powerful collection of ideas and tools than the last. What a great resource, especially for beginning teachers but also for us veterans!" L. Dee Fink, author, Creating Significant Learning ExperiencesThis third edition of Teaching at Its Best is successful at weaving the latest research on teaching and learning into what was already a thorough exploration of each topic. New information on how we learn, how students develop, and innovations in instructional strategies complement the solid foundation established in the first two editions." Marilla D. Svinicki, Department of Psychology, The University of Texas, Austin, and coauthor, McKeachie's Teaching Tips

IF YOU KNEW A BOOK WAS CURSED, WOULD YOU READ IT? When Ariel Manto uncovers a copy of The End of Mr Y in a second-hand bookshop, she can't believe her eyes. She's read about its author before, the outlandish Victorian scientist Thomas Lumas, and this is his most notorious, and rarest, book. It is also believed to hold a curse. Anyone who's ever read it, including Lumas, has disappeared without trace. With Mr Y under her arm, Ariel is thrust into an adventure of faith, physics, love, death, and everything in between. Part gothic mystery, part time-travelling love story, The End of Mr Y lies somewhere between Shadow of the Wind and Dr Who. Scarlett Thomas sends us on a wild and irresistible quest into our deepest selves and our biggest questions.