This book provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana), with particular emphasis on psychotic disorders. It outlines developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illness such as schizophrenia. A number of controversial issues are critically explored, including whether a discrete 'cannabis psychosis' exists, and whether cannabis can actually cause schizophrenia. Effects of cannabis on mood, notably depression, are reviewed, as are its effects on cognition. This book will be of interest to all members of the mental health team, as well as to neuroscientists and those involved in drug and alcohol research.

A few disorders have some of the same symptoms as schizophrenia including schizoaffective disorders, schizophreniform disorder, schizotypal and schizoid personality disorders, delusional disorder, and autism (schizophrenia spectrum disorders). Since the 2000 there has been significant progress in our understanding of the early presentations, assessment, suspected neuropathology, and treatment of these disorders. Recent technological breakthroughs in basic sciences hold promise for advancing our understanding of the pathophysiology of schizophrenia spectrum disorders. This collective monograph reviewers recent researches regarding the origins, onset, course, and outcome of schizophrenia spectrum disorders. In particular, this book will be illustrate new developments in terms of conceptual models, and research methodology, genetics and genomics, brain imaging and neurochemical studies, neurophysiology and information processing in schizophrenia spectrum disorders patients. Also will be highlighted new developments in our understanding of the childhood psychosis, prodromal and first-episode states, in treatment and rehabilitation. Thus, the purpose of this book is to provide up-to-date overview of the rapid advances made in the clinical and basic science studies supporting our understanding of the relationship between cerebral processes and clinical, cognitive and other presentations of the schizophrenia spectrum disorders. In addition, this book aims to monitor important research developments, which may be relevant to treatment, and rehabilitation of patients.

Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature.· Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

In this book, Murphy brings together a team of international experts to review cutting-edge scientific literature from the field of psychobiology and related disciplines which addresses important questions and broadens our understanding of substance use behaviours. The reader is introduced to the multi-faceted nature of substance use and misuse, and its growing need to be discussed across diverse disciplines and perspectives. The book also addresses important questions regarding public policy and professional practice in the context of different social and cultural environments, and comments on the methodological and ethical issues in substance use and misuse. Chapters explore a spectrum of substances, which include: cocaine, alcohol, ecstasy (MDMA), methamphetamine, synthetic cannabinoids, tobacco, ketamine, novel psychoactive substances, and vaping products. The use of these substances poses important questions for science and for society. This book is written to help academics, practitioners, and students in a variety of academic and professional disciplines answer those questions while staying up to date with the psychobiological literature. This is a vital resource for professionals and upper-level undergraduate and postgraduate students undertaking research in areas related to biological psychology, biology, health studies, and medicine.

Cannabis, marijuana, pot, ganja - it goes by many names — is by far the most widely used illegal substance, and accounts for more arrests than any other drug. Barely a week goes by without this drug appearing in the newpapers, and politicians have famously tied themselve in knots, trying to decide just how to deal with this recreational drug. While there have been many drug policy books on other substances - both legal and illegal, few have focused on this drug. Cannabis Policy: Moving beyond Stalemate is unique in providing the materials needed for deciding on policy about cannabis in its various forms. It reviews the state of knowledge on the health and psychological effects of cannabis, and its dangerousness relative to other drugs. It considers patterns and trends in use, the size and character of illicit markets, and the administration of current policies, including arrests and diversion to treatment, under the global prohibition regime. It looks at the experience of a number of countries which have tried reforming their regimes and softening prohibition, exploring the kinds of changes or penalties for use for possession: including depenalization, decriminalization, medical control, and different types of legalization. It evaluates such changes and draws on them to assess the effects on levels and patterns of use, on the market, and on adverse consequences of prohibition. For policymakers willing to look outside the box of the global prohibition regime, the book examines the options and possibilities for a country or group of countries to bring about change in, or opt out of, the global control system. Throughout, the book examines cannabis within a global frame, and provides in accessible form information which anyone considering reform will need in order to make decisions on cannabis policy (much of which is new or has not been readily available). This book will be essential for those involved in policymaking and be of interest to a wide range of readers interested in drugs and drug policy, as well as being an excellent supplementary text for university courses in criminology, policy science, social science, or public health. Published with the BECKLEY FOUNDATION PRESS

The spectrum of addiction disorders presents practitioners with numerous challenges—among them the widening gap between a growing evidence base and the translation of this knowledge into treatment outcomes. Addiction Medicine addresses this disconnect, clearly explaining the role of brain function in drug taking and other habit-forming behaviors, and applying this biobehavioral framework to the delivery of evidence-based treatment. Its state-of-the-art coverage provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding). Current behavioral and medical therapies are discussed in depth, and the book’s close attention to social context gives readers an added lens for personalizing treatment. An international panel of expert contributors offers the most up-to-date information on: Diagnosis and classification Neurobiological and molecular theories of addiction Behavioral concepts of addiction Clinical aspects of addiction to a wide range of substances, including opiates, stimulants, sedatives, hallucinogens, alcohol, nicotine, and caffeine Science-based treatment options: pharmacotherapy, pharmacogenetics, potential vaccines, brief and compliance-enhancing interventions, cognitive behavioral treatment, behavioral management, and other psychosocial interventions Behavioral addictions—including compulsive eating, Internet messaging, and hypersexuality—and their treatment Addiction in specific populations, including adolescents, the elderly, pregnant women, and health care professionals Legal, disability, and rehabilitation issues At once comprehensive and integrative, Addiction Medicine is an essential text and a practice-expanding tool for psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners.