Manufacturing systems don't exist in a vacuum, isolated from the rest of the company, but they are often managed that way. A truly effective, highly competitive manufacturing company integrates its manufacturing, marketing, sales, purchasing, and financial functions into a well-coordinated whole. Manufacturing at Warp Speed: Optimizing Supply Chain

Manufacturing systems don't exist in a vacuum, isolated from the rest of the company, but they are often managed that way. A truly effective, highly competitive manufacturing company integrates its manufacturing, marketing, sales, purchasing, and financial functions into a well-coordinated whole. Manufacturing at Warp Speed: Optimizing Supply Chain Financial Performance explains in detail how to coordinate all these functions to maximize sales revenue while controlling inventory and overhead costs. Ultimately, the effects of applying the new Simplified-Drum-Buffer-Rope (DBR II) introduced by the authors include dramatically faster manufacturing cycle times, shorter order-to-delivery lead times, higher on-time delivery reliability, and better customer satisfaction. The book gives you everything a typical production professional needs to implement this new DBR approach. A supplemental feature - the Management Interactive Case Study Simulator (MICSS) - is included with the book. Available for download via the CRC Press website, the simulator sets up a virtual company where you can test and practice the processes you learn in the book before implementing them in your organization. The book and software together constitute the complete package for learning how to streamline manufacturing operations. The first book available on second generation Drum-Buffer-Rope, Manufacturing at Warp Speed: Optimizing Supply Chain Financial Performance describes the simplest, most efficient methods for reducing manufacturing cycle time and increasing the speed of manufacturing yet devised. Fully illustrated, with numerous examples, case studies, and manufacturing scenarios, the book is so easy to read that even the novice can understand it. Correct use of this new method practically assures that your company has the competitive advantage.

In 2000, Schragenheim and Dettmer published the ground-breaking Manufacturing at Warp Speed. At the time, the cutting-edge ideas expressed were the original work of the authors and not well-known beyond the book‘s audience. In the years that followed, Dr. Eliyahu Goldratt, father of the Theory of Constraints (TOC), adopted their ideas, added his ow

A powerful story of how our nation’s leaders overcame the odds, saving the American people from the throes of a deadly pandemic. The prior record for vaccine development and distribution was approximately 4.5 years. Operation Warp Speed got the COVID-19 vaccine to the American people in less than 10 months. Operation Warp Speed did not happen by accident. It was the result of exceptional leadership, explicit strategy, and unprecedented teamwork. Author Paul Mango, the foremost leader of Operation Warp Speed and the former deputy chief of US Health and Human Services, chronicles the challenges and real dangers of developing the vaccine. From the beginning, two lead scientists, Dr. Moncef Slaoui and Dr. Debra Birx, fought head to head on which vaccines had the greatest probability of success. Tensions grew as the Army Materiel Command and the Center for Disease Control debated on whether public health agencies or the private sector would take over vaccine distribution. Mango details the largest hurdle for the Operation Warp Speed team: though Pfizer, the first distribution company to deliver the mRNA vaccine, sought aid from the Federal Government, they refused the government’s request to oversee safe manufacturing of the vaccine, eventually leading to a major scandal as Pfizer missed its contractual obligation to deliver 40 million doses by the end of 2020, the number of positive cases reaching a frightening peak all the while. In this harrowing, behind-the-scenes account of the most successful public-private partnership since World War II, we learn how the nation’s biggest leaders accomplished the impossible. Through sheer will and exceptional commitment, a small group of leaders fulfilled its mission, making the United States the only country in the world which could offer a vaccine to any citizen by April 2021, scarcely 14 months after the genetic identification of the virus.

This sequel to the bestselling Manufacturing at Warp Speed, refines and updates the former approach to production management. This is the first book to describe, in detail, the application of the TOC approach to assured availability in distribution, for both original equipment manufacturers and retailers. It addresses the new demands taken on when a firm offers to handle rush orders and addresses the issues surrounding availability, and the management of inventory as it moves through distribution systems.

In recent months, the Coronavirus Disease 2019 (COVID-19) pandemic has spread globally, with the United States now reporting the highest number of cases of any country in the world. Currently, there are few treatment options available to lessen the health impact of the disease and no vaccines or other prophylactic treatments to curb the spread of the virus. Researchers and product developers are testing numerous types of vaccines--both in the laboratory and in some early-stage testing in humans. This book answers frequently asked questions about current efforts related to research and development of vaccines, their regulation, and related policy issues.

The book begins with an overview of the constraint-based perspective on systems and organizations, commonly referred to as the theory of constraints or synchronous management. The first section will guide you through the fundamental principles and processes that are the backbone of the thinking process application tools. The second section contains the step-by-step guidelines for each of the five thinking process application tools. These tools utilize sufficient cause thinking and necessary condition thinking. Third section introduces two ways that two or more of the thinking process application tools are combined, providing robust processes for the understanding and communicating problems and solutions. This book can be used as a field guide to learning the five thinking process application tools as needed, based on their own particular issues. You will have a full understanding of the theory and practical application of these powerful processes, including when and when not to use each tool. The total benefit is not just to apply the thinking process, but to develop intuition and have the ability to combine logic and intuition in the same thinking process.