This book provides a comprehensive insight into this special form of image-guided interventional therapy and its indications. It begins by introducing the fundamental principles of radiotherapy, the most up-to-date guidelines and the interdisciplinary aspects of the technique and then expands to more practical aspects such as therapy planning, indications and the use of the technique for certain tumor types, including liver metastases, rare tumors, cerebral malignancies and prostate tumors. Written and edited by pioneers in this technique, the chapter’s outline results and numerous illustrated case studies from the daily routine of daily clinical practice providing an insightful guidance to this relatively new but growing method. This is an indispensable guide for oncologists, radiation therapists and radiologists, but also general practitioners and all other specialties, which have an oncological focus.

This handbook provides a clinically relevant, succinct, and comprehensive overview of image-guided brachytherapy. Throughout the last decade, the utility of image guidance in brachytherapy has increased to enhance procedural development, treatment planning, and radiation delivery in an effort to optimize safety and clinical outcomes. Organized into two parts, the book discusses physics and radiobiology principles of brachytherapy as well as clinical applications of image-guided brachytherapy for various disease sites (central nervous system, eye, head and neck, breast, lung, gastrointestinal, genitourinary, gynecologic, sarcoma, and skin). It also describes the incorporation of imaging techniques such as CT, MRI, and ultrasound into brachytherapy procedures and planning. Featuring procedural and anesthesia care, extensive images, contouring examples, treatment planning techniques, and dosimetry for the comprehensive treatment for each disease site, Handbook of Image-Guided Brachytherapy is a valuable resource for practicing radiation oncologists, physicists, dosimetrists, residents, and medical students.

This book analyzes liquid biopsy applications in cancer and other diseases. Chapters guide readers through the latest technologies and analysis methods for liquid biopsy,liquid biopsy in cancer, role of liquid biopsies in rheumatoid arthriti, cell-free circulating DNA profiling in patients with skin diseases, circulating non-coding RNAs, and exomes. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Liquid Biopsies: Methods and Protocols aims to attract more researchers and clinicians to study the diagnosis, immunotherapy, and prognosis of cancer and other diseases with liquid biopsy analysis.

Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications.

Cancer is a very aggressive disease and currently it has been considered a challenge to oncologists and cancer patients worldwide. Nowadays, several therapeutic strategies had improved toward last decades. Surgery is many times still the best curative treatment, mainly in early stage disease. However, Radiotherapy and chemotherapy acquired a main role in this scenario. Target therapies were introduced for medical oncology practice and are demonstrating a hallmark of a new era in cancer treatment. More recently, immunotherapy has been considered the novel cornerstone in cancer treatment. The 2nd edition of the International Manual of Oncology Practice (iMOP) emerged after the great success of the iMOP 1st edition as a reference for medical oncologists and medical residents in the field. In this edition, several chapters were revised and its addresses from the molecular issues of cancer sciences to the clinical practice in medical oncology. In addition, multiple choice questions and clinical cases were included in the main chapters in order to improve the reader learning. The book focuses systemic treatments in many areas of medical oncology, such as breast cancer, gastrointestinal, thoracic, urological oncology, head and neck tumors, bone tumors, sarcomas and palliative care. The topics herein discussed will provide the readers a step forward in the medical oncology practice understanding and give facilities for help in cancer patient treatments.

The first text to focus solely on quality and safety in radiotherapy, this work encompasses not only traditional, more technically oriented, quality assurance activities, but also general approaches of quality and safety. It includes contributions from experts both inside and outside the field to present a global view. The task of assuring quality

The Conference was established for the first time in 2023 as part of a programme of activities to sustain research culture environment and dissemination activities at the School of Engineering, Cardiff University, Cardiff United Kingdom. The conference served as a platform to celebrate advancements in various engineering domains researched at our School, and to explore and discuss further advancements in the diverse fields that define contemporary engineering. The structure of the conference programme reflected the multidimensional nature of our research and was built around the priority research areas for the school. 1. Sustainable Energy stands as a testament to our commitment to a greener, more efficient future. We aim to advance energy technology and play a key role in addressing the increasing demand for sustainable and low carbon technologies while reducing environmental impact and ensuring a sustainable environment. Our work helps to drive forward net-zero solutions for achieving the government carbon targets. 2. Advanced Manufacturing represents cutting-edge research into materials, systems and transformative technologies to transform engineering and economic performance in the transport, energy generation and manufacturing industries. Our research in this area focuses on developing smart materials and structures, and sustainable manufacturing processes that help create a sustainable and greener economy. 3. Civil Infrastructure takes centre stage as we improve the sustainability and resilience of infrastructure across the UK and the globe. We work on developing sustainable and resilient total lifecycle solutions across a wide range of domains including construction, structures, energy, geo-environmental and water infrastructure systems. From creating new nano-scale smart materials to macro-scale urban interventions. 4. Compound Semiconductors and Applications represents the cutting edge of electronics, a critical driver of progress in the digital age. We explore the latest developments in compound semiconductor materials, advanced characterisation techniques, quantum optics and novel circuit design methodologies and their diverse applications. We anticipate breakthroughs that will power the next generation of computing, communication, and sensing technologies. 5. Engineering for Health forms a cornerstone of our discussions, recognizing the pivotal role technology plays in revolutionizing healthcare. We are applying the latest research in medical engineering to push the boundaries in areas where innovation has the potential to transform patient care.