The book reports the results on the fate of POPs in the abiotic and biotic components of the aquatic environment North Pacific Ocean (include Russian part of North Pacific), possible health risks for coastal residents Pacific Ocean exposed to these hazardous pollutants are systematized. In particular, indicator organisms (fish, birds, and mammals), indicating the pollution of the region, were identified; the possible ways of xenobiotic transfer from the sea to the land are shown; the targets of POPs impact on living organisms were determined; the time of circulation of pollutants in the biosphere was determined; a list of “priority” toxicants for the region based on quality screening was compiled; the risks to human health from the consumption of contaminated aquatic organisms were assessed; the levels of POPs in the human body were measured. The book is interesting for specialists in the agro-industrial complex, aquaculture and medicine, teachers and graduate students of universities, researchers, which interested in the problems of persistent organic pollutants (POPs). There are no similar books on the study of POPs in the Russian part of the Pacific Ocean in the world literature. This book is useful to scientists of the world who study the fate of POPs.