"Ebert has herein assembled an enormous body of knowledge about California's 43 shark species ranging from shark and human behavior to taxonomic minutiae, along with up-to-date explanations of their ecology, status and fisheries. More importantly, his Herculean effort includes the often-overlooked 25 species of skates, rays and chimaeras. That, along with the fine illustrations of Mat Squillante, should answer any question that a student, diver, natural history buff, or recreational or commercial fisher might ask."—John E. McCosker, coauthor of Great White Shark "The timing of this publication is ideal given the status of some of California's elasmobranch populations and the need for a deeper understanding of their biology, ecology, and fishery management. The book is a comprehensive treatment—if one wants to find out the latest information on any species of shark or ray off California, this is the place to go. An outstanding work!"—Gregor M. Cailliet, Professor, Moss Landing Marine Laboratories, and Director, Pacific Shark Research Center

This volume addresses challenging new questions surrounding stem cell-based chimera research. This book is organized into three parts: Part One provides readers with a summary of different human donor cell types. The chapters in this section discuss ways to evaluate new types of pluripotent stem cells; the derivation of naïve and primed pluripotent stem cells from mouse preimplantation embryos; and the ethical and regulatory complexities of informed consent for the procurement of somatic cells. Part Two discusses methods for generating chimeras. The chapters here look at chick models and human-chick organizer grafts; generating human-pig interspecies chimeras; and techniques for transplanting mouse neural stem cells into a mouse disease model for stroke. Part Three concludes the book with a look at ongoing ethical controversies and new scientific directions. Chapters in this part cover the ethics of crossing the xenobarrier; animal welfare; experimentation with spermatogonial stem cells; and cautious approaches to human-monkey chimera studies to further understand complex human brain disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Chimera Research: Methods and Protocols is a valuable resource for scientists interesting in using chimeras as a research tool while also taking into consideration their complex ethical scopes.

The Teeth of Non-Mammalian Vertebrates is the first comprehensive publication devoted to the teeth and dentitions of living fishes, amphibians and reptiles. The book presents a comprehensive survey of the amazing variety of tooth forms among non-mammalian vertebrates, based on descriptions of approximately 400 species belonging to about 160 families. The text is lavishly illustrated with more than 600 high-quality color and monochrome photographs of specimens gathered from top museums and research workers from around the world, supplemented by radiographs and micro-CT images. This stimulating work discusses the functional morphology of feeding, the attachment of teeth, and the relationship of tooth form to function, with each chapter accompanied by a comprehensive, up-to-date reference list. Following the descriptions of the teeth and dentitions in each class, four chapters review current topics with considerable research activity: tooth development; tooth replacement; and the structure, formation and evolution of the dental hard tissues. This timely book, authored by internationally recognized teachers and researchers in the field, also reflects the resurgence of interest in the dentitions of non-mammalian vertebrates as experimental systems to help understand genetic changes in evolution of teeth and jaws. - Features more than 600 images, including numerous high-quality photographs from internationally-recognized researchers and world class collections - Offers guidance on tooth morphology for classification and evolution of vertebrates - Provides detailed coverage of the dentition of all living groups of non-mammalian vertebrates

The definitive field guide to all the sharks, rays and chimaeras of the European Atlantic and Mediterranean The waters of the northeast Atlantic and Mediterranean Sea are home to an amazing variety of sharks, rays and chimaeras. This comprehensive and easy-to-use field guide covers all 146 species found in the Mediterranean, the waters of the European Atlantic and Iceland, along all the Scandinavian coasts, in the Black Sea and as far south as the Canary Islands. Detailed species accounts describe key identification features, habitat, biology and status. Every species account comes with a colour distribution map, a depth guide, at-a-glance icons and colour illustrations. This must-have field guide also features illustrated key guides that enable you to accurately identify down to species, comparison plates of similar species, illustrations of eggcases where known and plates of teeth. The first field guide to cover all 146 species Features hundreds of colour illustrations, photos, maps and diagrams Describes key features, habitat, biology and status Includes depth guides, at-a-glance icons, key guides and teeth plates

Scientists elucidate the astounding collective sensory capacity of Earth and its evolution through time.