This book tells about kitchen chemistry.

Determined to become a wizard, twelve-year-old Randal is delighted to be accepted into the famed School of Wizardry, but his apprenticeship is marred when he realizes that one of the master wizards is using evil spells to destroy the school and gain supreme power.

The kids in Ms. Frizzle's class are getting ready for the Wild Weather Show. To prepare, they take a field trip to the Weatherama Amusement Park. The class finds out just how wild weather can be when they accidentally fly right into a powerful tornado.

Oh, no! Wanda's best friend, Bella the bullfrog, is missing. The class wants to help look for her. Ms. Frizzle says, "The best way to find a frog is to be a frog!" So, the kids take a ride on the Magic School Bus. Join them as they shrink to frog size and learn all about animal habitats!

Everybody agrees that mold is just disgusting, until the class goes on a field trip inside a rotting log. They discover that all the dead-looking stuff is actually alive...and it's pretty neat after all. Join the class on their "rotten" adventure, and learn about how nature recycles through decomposition.

It's beach day, and the whole class is excited. Everyone except Arnold and Keesha, that is. They forgot their report on two beach things that go together. All Arnold and Keesha have is a tunafish sandwich and some smelly green pond scum. What could those two things possibly have in common? "The best way to learn about something is to jump right in," Ms. Frizzle announces. A second later the bus dives right into the ocean! Come on an underwater adventure and learn about food chains.

Ms. Frizzle takes her class on a field trip through the town's electrical wires so they can learn how electricity is generated and how it is used.