A violent reimagining of the classic assassin-and-child story by the writer of the acclaimed film Arrival! AD 2100: The world has been devastated by a manmade plague. Young Daisy Ogami is infected but unaffected--naturally immune. In her blood can be found a cure that will save humanity. But the remaining world powers are concerned less with preserving humanity and more with being the first nation to return to power. Unfortunately for them, Daisy has a protector . . . a loyal android named Itto. In a violent reimagining of the classic assassin-and-child story of Kazuo Koike and Goseki Kojima's Lone Wolf and Cub, Itto and Daisy set out across the Plague Lands, looking for a way to save the world while pursued by plague victims, ruthless mercenaries, and the armored soldiers of dying nations. Pity those who catch up with them . . . Collects Lone Wolf 2100: Chase the Setting Sun 1-4.

Soldiers have come, sent by governments fearful that another will be the first to benefit from a vaccine harvested from young Daisy Ogami's blood. In the middle of the Pacific, an ambush takes place. But Daisy's protector, the android Itto, is ready with a counterambush . . . The blood spilled will not be Daisy's! Hell in the Pacific! A reimagining of the classic assassin-and-child tale originated in Lone Wolf and Cub.

The fate of the human race comes down to a final battle on the coast of Japan! Daisy Ogami holds the key to a cure for a killer virus, but only Itto, her android bodyguard, can protect her from those who would let the plague continue!

Young Daisy Ogami's blood carries the cure to the plague that has devastated the world. Itto, Daisy's android protector, has gone in search of a country that will use the cure fairly. Unfortunately, the remaining world powers all want the cure for themselves—and one has sent soldiers to insure that happens! A reimagining of the classic assassin-and-child tale originated in Lone Wolf and Cub.

The last real man on Earth may be an android! AD 2100: A devastating manmade plague is turning the human race into cannibalistic monsters known as the Thrall. But there is hope: young Daisy Ogami's blood holds the secret to a cure—if Itto, her android protector, can get her to a place where it can be extracted! Screenwriter Eric Heisserer retools Lone Wolf 2100!

From the writer of the acclaimed film Arrival! A galactic empire hunts a race of shape shifters prophesied to overthrow its rule. When orphaned teenager Spry discovers that he is one of the hunted—a Shaper—he must learn to use his newfound abilities to escape the empire’s prime enforcer, Tor Ajax, and save his entire race! * Screenwriter Eric Heisserer brings his cinematic vision to comics! * A timeless tale for a new generation! * In the tradition of Arthurian legends and Star Wars.