Apply cutting-edge expertise to manage your patients’ scarring issues! Scarring and fibrosis affect millions of people worldwide, and can be devastating both physically and psychologically, whether they result from major trauma such as burns or common conditions such as acne. Put today’s most advanced clinical approaches to work for your patients with The Scar Book: Formation, Mitigation, Rehabilitation, and Prevention! A multidisciplinary team of leading world experts presents the state of the art in scar pathophysiology and treatment, breaking down the barriers between medical disciplines to provide unprecedented holistic guidance.

Une vraie fausse biennale imaginée par Maurizio Cattelan sur le site de l'île antillaise de St. Kitts. Des artistes dans un hôtel, partagent les repas, la plage, les bains, effaçant toute trace d'art...

In most mathematics textbooks, the most exciting part of mathematics - the process of invention and discovery - is completely hidden from the student. The aim of Knots and Surfaces is to change all that. Knots and Surfaces guides the reader through Euler's formula, one and two-sided surfaces, and knot theory using games and examples. By means of a series of carefully selected tasks, this book leads the reader on to discover some real mathematics. There are no formulas to memorize; no procedures to follow. This book is a guide to the mathematics - it starts you in the right direction and brings you back if you stray too far. Discovery is left to you. This book is aimed at undergraduates and those with little background knowledge of mathematics.

Mathematics is discovered by looking at examples, noticing patterns, making conjectures, and testing those conjectures. Once discovered, the final results get organized and put in textbooks. The details and the excitement of the discovery are lost. This book introduces the reader to the excitement of the original discovery. By means of a wide variety of tasks, readers are led to find interesting examples, notice patterns, devise rules to explain the patterns, and discover mathematics for themselves. The subject studied here is the mathematics behind the idea of symmetry, but the methods and ideas apply to all of mathematics. The only prerequisites are enthusiasm and a knowledge of basic high-school math. The book is only a guide. It will start you off in the right direction and bring you back if you stray too far. The excitement and the discovery are left to you.

The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.

Retraces in sailboat or small plane the routes taken by the Argonauts, Ulysses, Columbus, Vespucci, Magellan, Elcano, and the Portuguese and Spanish explorers of the Americas.