"Science tends to generalize, and generaliza tions mean simplifications . . . . And generaliza tions are also more satisfying to the mind than details. Of course, details and generalizations must be in proper balance: Generalizations can be reached only from details, while it is the generalization which gives value and interest to the detail:' . . . (A. Szent-Gyorgy, Science 1964) The first edition of this book, published in German as Tabak abhiingigkeit in 2001, was prompted by the fact that no single volume was available in Germany or elsewhere summarising the adverse repercussions of cigarette smoking on human health. As far as my own research was able to ascertain, the last comprehensive work dealing with this subject was writ ten in Germany by the Dresden internist, F. Lickint, whose Tabak und Organismus was published in 1939 by the Hip pokrates-Verlag. All subsequent monographs in this field have tended to focus on detailed aspects, and there has been no shortage of publications on subjects such as how smokers can quit smoking, healthy eating for smokers etc. Friends and colleagues abroad have urged me to prepare an English language version of Tabakabhiingigkeit. In gladly complying with this suggestion, I have intentionally prepared an up dated and slightly enlarged new edition, taking account of the rapidly proliferating literature on the subject up to the start of 2002. The harmful sequelae of smoking are played down by politicians in many industrialised countries, including Ger many.

This book provides a state-of-the-art look at the applied biomechanics of accidental injury and prevention. The editors, Drs. Narayan Yoganandan, Alan M. Nahum and John W. Melvin are recognized international leaders and researchers in injury biomechanics, prevention and trauma medicine. They have assembled renowned researchers as authors for 29 chapters to cover individual aspects of human injury assessment and prevention. This third edition is thoroughly revised and expanded with new chapters in different fields. Topics covered address automotive, aviation, military and other environments. Field data collection; injury coding/scaling; injury epidemiology; mechanisms of injury; human tolerance to injury; simulations using experimental, complex computational models (finite element modeling) and statistical processes; anthropomorphic test device design, development and validation for crashworthiness applications in topics cited above; and current regulations are covered. Risk functions and injury criteria for various body regions are included. Adult and pediatric populations are addressed. The exhaustive list of references in many areas along with the latest developments is valuable to all those involved or intend to pursue this important topic on human injury biomechanics and prevention. The expanded edition will interest a variety of scholars and professionals including physicians, biomedical researchers in many disciplines, basic scientists, attorneys and jurists involved in accidental injury cases and governmental bodies. It is hoped that this book will foster multidisciplinary collaborations by medical and engineering researchers and academicians and practicing physicians for injury assessment and prevention and stimulate more applied research, education and training in the field of accidental-injury causation and prevention.

Cadmium is widely dispersed in the environment. Human exposure to low levels occur as a result of natural processes as well as human activities such as mining, smelting, fossil fuel combustion and industrial use. Pollution of the general environment by cadmium has as yet only been related to the development of human disease in some special situations, such as itai-itai disease and renal dysfunction in Belgium and in China. However, the possibility of more widespread contamination and greater mobility of cadmium in the environment on the one hand and the advent of new data concerning the carcinogenicity of cadmium on the other, make this review of the "state of the art" in human risk identification and assessment timely. Recent studies on human exposure to cadmium metabolism and toxicology, renal dysfunction and related effects, and experimental and epidemiological evidence for carcinogenicity of cadmium are described.