In collaboration with the Consulting Editors, Ranjan K. Thakur and Andrea Natale, Drs. Dhanunjaya Lakkireddy, David R. Holmes Jr., and Saibal Kar have assembled an issue of Cardiac Electrophysiology Clinics on Left Atrial Appendage. Topics include, but are not limited to, why we have an atrial appendage, thromboembolism in AF, role of LAA in systemic homeostasis, history of LAA closure, impact of LAA closure on systemic thromboembolization, perirprocedural imaging, anatomical considerations for epicardial and endocardial appendage closure, epicardial vs endocardial closure, technical considerations of endocardial and epicardial closure, surgical LAA occlusion, post procedural management, AF patients undergoing ablation, and more.

In this issue of Cardiac Electrophysiology Clinics, guest editor Dr. Matthew J. Daniels brings his considerable expertise to the topic of Left Atrial Appendage Occlusion. Top experts in the field discuss topics such as pre-cath laboratory planning for left atrial appendage occlusion: optional or essential; the case for intracardiac echo to guide left atrial appendage closure; follow-up imaging after left atrial appendage occlusion: something or nothing and for how long?; left atrial appendage closure: what the evidence does and does not reveal; and more. - Contains 11 practice-oriented topics including the strengths and weaknesses of the LAA covering disc occluders; left atrial appendage occlusion strengths and weaknesses of the lobe-only occluder concept in theory and in practice; the strengths and weaknesses of left atrial appendage ligation or exclusion (LARIAT, AtriaClip, Surgical Suture); the future of LAAC—in 5, 10, and 20 years; and more. - Provides in-depth clinical reviews on left atrial appendage occlusion, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Mohammad Shenasa, Prashanthan Sanders, and Stanley Nattel, is dedicated to Risk Factors in Atrial Fibrillation: Appraisal of AF Risk Stratification. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to, Epidemiology of Atrial Fibrillation; Hypertension, Prehypertension, Hypertensive Heart Disease and Atrial Fibrillation; Pulmonary Disease, Pulmonary Hypertension and Atrial Fibrillation; Heart Failure with Preserved (HFpEF) and Reduced (HFrEF) LV Systolic Function, Diastolic Dysfunction; Coronary Artery Disease; ECG and Echo Abnormalities in Patients with Atrial Fibrillation Risk Factors; Diabetes and Endocrine Disorders; Obesity and Metabolic Syndrome in Atrial Fibrillation; Renal Disease; Sleep Apnea and Atrial Fibrillation; Channelopathies in Atrial Fibrillation; Implications of Inflammation and Myocardial Fibrosis in Atrial Fibrillation; Role of Biomarkers in Atrial Fibrillation; Left Ventricular Hypertrophy and Other Cardiomyopathies in Atrial Fibrillation; Atrial Fibrillation in Valvular Heart Disease; Atrial Fibrillation in Adult Congenital Heart Disease; Exercise and Athletic Activity in Atrial Fibrillation; Post-op Atrial Fibrillation; Autonomic Dysfunction and Neurohormonal Disorders in Atrial Fibrillation; Social Risk Factors; Atrial Fibrillation and Stroke; Screening for Atrial Fibrillation Risk Factors; Primary Care and Internists Perspective on Atrial Fibrillation Risk Factors; and Lifestyle as a Risk Factor for Atrial Fibrillation.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Fermin C. Garcia, Luis C. Saenz, and Pasquale Santangeli, is dedicated to Intracardiac Echo Imaging in Atrial and Ventricular Arrhythmia Ablation. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to: How to use intracardiac echography to recognize normal cardiac anatomy, Intracardiac echography to guide catheter ablation of ventricular arrhythmias in ischemic cardiomyopathy, Intracardiac echography to guide ablation of parahisian arrhythmias, Utility of ICE to guide transseptal catheterization for different EP procedures, Intracardiac echography to guide catheter ablation of atrial fibrillation, Role of intracardiac echography for transcatheter occlusion of left atrial appendage, Intracardiac echography to guide catheter ablation of idiopathic ventricular arrythmias, Intracardiac echography to guide catheter ablation of ventricular arrhythmias in non-ischemic cardiomyopathy, Intracardiac echography to guide mapping and ablation of arrhythmias in congenital heart disease patients, Prevention and early recognition of complications during catheter ablation by Intracardiac echography, Intracardiac echography to evaluate radiofrequency lesion creation and Image integration using intracardiac echography and 3-D reconstruction for mapping and ablation of atrial and ventricular arrhythmias.

Because atrial fibrillation promotes the formation of blood clots that can travel to the brain and block an artery, atrial fibrillation independently increases the risk of ischemic stroke four-to-five-fold. In this issue expert authors review drug therapies for stroke prevention, use of the new anticoagulants, ablation strategies for stroke prevention, LAA closure for stroke prevention, stroke in heart rhythm device patients, transesophageal echo in atrial fibrillation, and other topics important to the management of this serious complication.

This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Jason Bradfield and Kalyanam Shivkumar, is dedicated to Epicardial Interventions in Electrophysiology. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to, Anatomy of the Pericardial Space, Techniques for Percutaneous Access, Peri-operative Imaging to Guide Epicardial Mapping and Ablation, Epicardial Ablation of Idiopathic Ventricular Tachycardia, Epicardial Ablation of Ischemic Ventricular Tachycardia, Epicardial Ablation of Non-ischemic Ventricular Tachycardia, Epicardial Ablation of Arrhythmogenic Right Ventricular Cardiomyopathy, Epicardial Ablation of Ventricular Arrhythmia secondary to Brugada Syndrome, Epicardial Ablation of Supraventricular Tachycardia, Epicardial Ablation of Atrial Fibrillation, Hybrid Surgical Epicardial Ablation, Epicardial Ablation via the Arterial and Venous System, Epicardial Ablation Biophysics and novel Radiofrequency Energy Delivery Techniques, Epicardial Ablation Complications, and The Future of Epicardial Interventions.