This book presents an integrated and holistic discussion on cadmium, lead and mercury toxicity in aquatic environments, expanding general concepts on chemical speciation effects and exploring specific environmental toxicological issues, exposure routes, and bioanalytical approaches for their determination and assessments on their intracellular deleterious effects. It contains worldwide and regional aspects on cadmium, lead and mercury occurrence, fate, and toxicity, addressing key environmental exposure and health risk concerns to both humans and aquatic organisms. Our book is of interest to anyone conducting research in the broad fields of oceanography, geochemistry, ecotoxicology, and environmental and public health.

This book details the state-of-the art in early warning monitoring of anthropogenic pollution of soil and water. It is unique with regard to its complex, multidisciplinary, mechanistic approach. Top scientists establish links and strengthen weak connections between specific fields in biology, microbiology, chemistry, biochemistry, toxicology, sensoristics, soil science and hydrogeology.

The need for a volume dealing with the concept of indicator organisms became evident during a symposium on the subject, organized by the present editors for the Southern California Academy of Sciences. Ques tions were posed about the appropriate uses of indicator organisms and the "rules" governing the application of the indicator concept to particular problems. For example, how does one distinguish true indicators from biological anomalies? What kinds of organisms can appropriately be associated with conditions and events at various scales in time and space? To what extent does one species represent other species in the same environmental setting? Can the indicator concept be applied to the context of modern sampling and analytical technology? How can anthropogenic perturbations be distinguished from natural phenomena? How can unlike matrices from differing data bases with differing scales best be matched? Such questions are especially pertinent in today's research environment. The use of indicator organisms, while certainly not new, is the corner stone for much scientific research. In the past two decades, indicator organisms have played increasingly important roles in the development and implementation of public policy. In particular, indicator organisms are being used to describe local environments and natural or anthropogenic perturbations to them, although there are pitfalls and problems associated with those usages. A growing number of nonbiologists, including physical oceanographers, find indicator organisms helpful, and sometimes essential, to their re search.

This book presents an integrated and holistic discussion on cadmium, lead and mercury toxicity in aquatic environments, expanding general concepts on chemical speciation effects and exploring specific environmental toxicological issues, exposure routes, and bioanalytical approaches for their determination and assessments on their intracellular deleterious effects. It contains worldwide and regional aspects on cadmium, lead and mercury occurrence, fate, and toxicity, addressing key environmental exposure and health risk concerns to both humans and aquatic organisms. Our book is of interest to anyone conducting research in the broad fields of oceanography, geochemistry, ecotoxicology, and environmental and public health.

This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pathophysiology of itai-itai disease, a serious condition caused by Cd pollution. Cadmium -New Aspects in Human Disease, Rice Contamination, and Cytotoxicity- is a valuable resource for scientists involved in heavy metal toxicology, botanical sciences, and regulatory sciences. Addressing the features of Cd pollution in the past and in the present, as well as future perspectives, this is a must-have book for students, researchers and practitioners interested in global and local metal pollution.

Reviewed and summarised research results and information from both developed and developing countries including Asia-Pacific, Australasia and other parts of the world.

Mercury is widespread in our environment. Methylmercury, one organic form of mercury, can accumulate up the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Combustion processes, especially coal-fired power plants, are major sources of mercury contamination in the environment. The U.S. Environmental Protection Agency (EPA) is considering regulating mercury emissions from those plants. Toxicological Effects of Methylmercury reviews the health effects of methylmercury and discusses the estimation of mercury exposure from measured biomarkers, how differences between individuals affect mercury toxicity, and appropriate statistical methods for analysis of the data and thoroughly compares the epidemiological studies available on methylmercury. Included are discussions of current mercury levels on public health and a delineation of the scientific aspects and policy decisions involved in the regulation of mercury. This report is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report also provides an excellent example of the implications of decisions in the risk assessment process for a larger audience.